Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 732
MIM: 120960
HGNC: 1353
Ensembl: ENSG00000021852
Variants:
dbSNP: 732
ClinVar: 732
TCGA: ENSG00000021852
COSMIC: C8B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000021852 | ENST00000371237 | P07358 |
| ENSG00000021852 | ENST00000535057 | F5GY80 |
| ENSG00000021852 | ENST00000543257 | F5H7G1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29532326 | 2018 | Comprehensive Proteoform Characterization of Plasma Complement Component C8αβγ by Hybrid Mass Spectrometry Approaches. | 13 |
| 29532326 | 2018 | Comprehensive Proteoform Characterization of Plasma Complement Component C8αβγ by Hybrid Mass Spectrometry Approaches. | 13 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
| 20406964 | 2010 | Risk of meningioma and common variation in genes related to innate immunity. | 21 |
| 20438785 | 2010 | Polymorphisms in innate immunity genes and risk of childhood leukemia. | 12 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
| 20406964 | 2010 | Risk of meningioma and common variation in genes related to innate immunity. | 21 |
| 20438785 | 2010 | Polymorphisms in innate immunity genes and risk of childhood leukemia. | 12 |
| 19162005 | 2009 | Response gene to complement 32 is required for C5b-9 induced cell cycle activation in endothelial cells. | 37 |
| 19344414 | 2009 | Risk of non-Hodgkin lymphoma in association with germline variation in complement genes. | 9 |
| 19423540 | 2009 | Common variation in genes related to innate immunity and risk of adult glioma. | 35 |
| 19864026 | 2009 | Involvement of the c-jun N-terminal kinases JNK1 and JNK2 in complement-mediated cell death. | 13 |
| 19162005 | 2009 | Response gene to complement 32 is required for C5b-9 induced cell cycle activation in endothelial cells. | 37 |
| 19344414 | 2009 | Risk of non-Hodgkin lymphoma in association with germline variation in complement genes. | 9 |
| 19423540 | 2009 | Common variation in genes related to innate immunity and risk of adult glioma. | 35 |
Citation
Dessen P
C8B (complement C8 beta chain)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61278/c8b-(complement-c8-beta-chain)
