Identity
HGNC
LOCATION
10p12.33
LOCUSID
ALIAS
CAB2,CACNLB2,CAVB2,MYSB
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 783
MIM: 600003
HGNC: 1402
Ensembl: ENSG00000165995
Variants:
dbSNP: 783
ClinVar: 783
TCGA: ENSG00000165995
COSMIC: CACNB2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443459 | Atrial Fibrillation | Disease | Literature, MultilinkAnnotation | associated | 24727801 | ||
| PA448871 | celecoxib | Chemical | Pathway | associated | 22336956 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33491517 | 2022 | Association study of hypertension susceptibility genes ITGA9, MOV10, and CACNB2 with preeclampsia in Chinese Han population. | 0 |
| 35894107 | 2022 | Epigenetic mechanism of L-type calcium channel β-subunit downregulation in short QT human induced pluripotent stem cell-derived cardiomyocytes with CACNB2 mutation. | 3 |
| 35955449 | 2022 | A Preclinical Study on Brugada Syndrome with a CACNB2 Variant Using Human Cardiomyocytes from Induced Pluripotent Stem Cells. | 5 |
| 35969184 | 2022 | Bipolar-associated miR-499-5p controls neuroplasticity by downregulating the Cav1.2 subunit CACNB2. | 5 |
| 33491517 | 2022 | Association study of hypertension susceptibility genes ITGA9, MOV10, and CACNB2 with preeclampsia in Chinese Han population. | 0 |
| 35894107 | 2022 | Epigenetic mechanism of L-type calcium channel β-subunit downregulation in short QT human induced pluripotent stem cell-derived cardiomyocytes with CACNB2 mutation. | 3 |
| 35955449 | 2022 | A Preclinical Study on Brugada Syndrome with a CACNB2 Variant Using Human Cardiomyocytes from Induced Pluripotent Stem Cells. | 5 |
| 35969184 | 2022 | Bipolar-associated miR-499-5p controls neuroplasticity by downregulating the Cav1.2 subunit CACNB2. | 5 |
| 31887354 | 2020 | Autism-associated mutations in the Ca(V)β(2) calcium-channel subunit increase Ba(2+)-currents and lead to differential modulation by the RGK-protein Gem. | 5 |
| 32158010 | 2020 | CACNB2 rs11013860 polymorphism correlates of prefrontal cortex thickness in bipolar patients with first-episode mania. | 1 |
| 31887354 | 2020 | Autism-associated mutations in the Ca(V)β(2) calcium-channel subunit increase Ba(2+)-currents and lead to differential modulation by the RGK-protein Gem. | 5 |
| 32158010 | 2020 | CACNB2 rs11013860 polymorphism correlates of prefrontal cortex thickness in bipolar patients with first-episode mania. | 1 |
| 30395415 | 2019 | Bifid T waves on the ECG and genetic variation in calcium channel voltage-dependent beta 2 subunit gene (CACNB2) in acute Kawasaki disease. | 3 |
| 30744588 | 2019 | Variation in the CACNB2 gene is associated with functional connectivity of the Hippocampus in bipolar disorder. | 6 |
| 31439644 | 2019 | CACNB2 Is a Novel Susceptibility Gene for Diabetic Retinopathy in Type 1 Diabetes. | 11 |
Citation
Dessen P
CACNB2 (calcium voltage-gated channel auxiliary subunit beta 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61369/cacnb2-(calcium-voltage-gated-channel-auxiliary-subunit-beta-2)
