CALHM1 (calcium homeostasis modulator 1)

2014-11-01  

Identity

HGNC
LOCATION
10q24.33
LOCUSID
ALIAS
FAM26C

Other Information

Locus ID:

NCBI: 255022
MIM: 612234
HGNC: 23494
Ensembl: ENSG00000185933

Variants:

dbSNP: 255022
ClinVar: 255022
TCGA: ENSG00000185933
COSMIC: CALHM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185933ENST00000329905Q8IU99

Expression (GTEx)

0
1
2
3
4

Pathways

PathwaySourceExternal ID
Taste transductionKEGGko04742
Taste transductionKEGGhsa04742

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
331990242021Thermosensitivity of the voltage-dependent activation of calcium homeostasis modulator 1 (calhm1) ion channel.1
331990242021Thermosensitivity of the voltage-dependent activation of calcium homeostasis modulator 1 (calhm1) ion channel.1
267007972016Genetic association of CALHM1 rs2986017 polymorphism with risk of Alzheimer's disease: a meta-analysis.0
269444522016Calcium homeostasis modulator 1 gene P86L polymorphism and the risk for alzheimer's disease: A meta-analysis.2
267007972016Genetic association of CALHM1 rs2986017 polymorphism with risk of Alzheimer's disease: a meta-analysis.0
269444522016Calcium homeostasis modulator 1 gene P86L polymorphism and the risk for alzheimer's disease: A meta-analysis.2
264166462015CALHM1 and its polymorphism P86L differentially control Ca²⁺homeostasis, mitogen-activated protein kinase signaling, and cell vulnerability upon exposure to amyloid β.7
264166462015CALHM1 and its polymorphism P86L differentially control Ca²⁺homeostasis, mitogen-activated protein kinase signaling, and cell vulnerability upon exposure to amyloid β.7
243260432014No association between polymorphisms in the calcium homeostasis modulator 1 gene and mesial temporal lobe epilepsy risk in a Chinese population.1
246307572014Lack of association between CALHM1 p.P86L variation and Alzheimer's disease in the Han Chinese population.1
253866462014Effect of the CALHM1 G330D and R154H human variants on the control of cytosolic Ca2+ and Aβ levels.8
243260432014No association between polymorphisms in the calcium homeostasis modulator 1 gene and mesial temporal lobe epilepsy risk in a Chinese population.1
246307572014Lack of association between CALHM1 p.P86L variation and Alzheimer's disease in the Han Chinese population.1
253866462014Effect of the CALHM1 G330D and R154H human variants on the control of cytosolic Ca2+ and Aβ levels.8
233000802013Structural and functional similarities of calcium homeostasis modulator 1 (CALHM1) ion channel with connexins, pannexins, and innexins.59

Citation

Dessen P

CALHM1 (calcium homeostasis modulator 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61387/calhm1-(calcium-homeostasis-modulator-1)