CALHM2 (calcium homeostasis modulator family member 2)

2014-11-01  

Identity

HGNC
CALHM2
LOCATION
10q24.33
LOCUSID
51063
ALIAS
FAM26B
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51063
MIM: 612235
HGNC: 23493
Ensembl: ENSG00000138172

Variants:

dbSNP: 51063
ClinVar: 51063
TCGA: ENSG00000138172
COSMIC: CALHM2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138172ENST00000260743Q9HA72
ENSG00000138172ENST00000369788Q9HA72

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
319885242020Structure and assembly of calcium homeostasis modulator proteins.5
317765152019The structures and gating mechanism of human calcium homeostasis modulator 2.4
201645732010Genetic association between CALHM1, 2, and 3 polymorphisms and Alzheimer's disease in a Japanese population.3
201645732010Genetic association between CALHM1, 2, and 3 polymorphisms and Alzheimer's disease in a Japanese population.3

Citation

Dessen P

CALHM2 (calcium homeostasis modulator family member 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61388/calhm2-(calcium-homeostasis-modulator-family-member-2)