CAPRIN2 (caprin family member 2)

2014-11-01  

Identity

HGNC
CAPRIN2
LOCATION
12p11.21
LOCUSID
65981
ALIAS
C1QDC1,EEG-1,EEG1,RNG140
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 65981
MIM: 610375
HGNC: 21259
Ensembl: ENSG00000110888

Variants:

dbSNP: 65981
ClinVar: 65981
TCGA: ENSG00000110888
COSMIC: CAPRIN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000110888ENST00000298892Q6IMN6
ENSG00000110888ENST00000395805Q6IMN6
ENSG00000110888ENST00000417045Q6IMN6
ENSG00000110888ENST00000433722H3BM22
ENSG00000110888ENST00000454014Q6IMN6
ENSG00000110888ENST00000537108F5H142
ENSG00000110888ENST00000537553H0YGG3
ENSG00000110888ENST00000540436F5H7T6
ENSG00000110888ENST00000540584F5GXI7
ENSG00000110888ENST00000541765F5GZX3
ENSG00000110888ENST00000542550F5H5J8
ENSG00000110888ENST00000543380F5GYA1
ENSG00000110888ENST00000548676H0YID4

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
187625812008Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation.26
145931122004Cloning and characterization of a gene expressed during terminal differentiation that encodes a novel inhibitor of growth.15
253319572014Structural insights into the C1q domain of Caprin-2 in canonical Wnt signaling.11
278215872016Activation/Proliferation-associated Protein 2 (Caprin-2) Positively Regulates CDK14/Cyclin Y-mediated Lipoprotein Receptor-related Protein 5 and 6 (LRP5/6) Constitutive Phosphorylation.6

Citation

Dessen P

CAPRIN2 (caprin family member 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61413/caprin2-(caprin-family-member-2)