CBR4 (carbonyl reductase 4)

2014-11-01  

Identity

HGNC
LOCATION
4q32.3
LOCUSID
ALIAS
SDR45C1
FUSION GENES

Other Information

Locus ID:

NCBI: 84869
HGNC: 25891
Ensembl: ENSG00000145439

Variants:

dbSNP: 84869
ClinVar: 84869
TCGA: ENSG00000145439
COSMIC: CBR4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000145439ENST00000306193Q8N4T8
ENSG00000145439ENST00000504480Q8N4T8
ENSG00000145439ENST00000504561H0Y962
ENSG00000145439ENST00000506808D6RGF2
ENSG00000145439ENST00000507752D6RJF4
ENSG00000145439ENST00000510042D6RAV8

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
19571038200917beta-hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS.16
190009052008Human carbonyl reductase 4 is a mitochondrial NADPH-dependent quinone reductase.2

Citation

Dessen P

CBR4 (carbonyl reductase 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61446/cbr4-(carbonyl-reductase-4)