CCL4L2 (C-C motif chemokine ligand 4 like 2)

2014-11-01  

Identity

HGNC
LOCATION
17q12
LOCUSID
ALIAS
AT744.2,CCL4L,SCYA4L,SCYQ4L2

Other Information

Locus ID:

NCBI: 9560
MIM: 610757
HGNC: 24066
Ensembl: ENSG00000276070

Variants:

dbSNP: 9560
ClinVar: 9560
TCGA: ENSG00000276070
COSMIC: CCL4L2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000276070ENST00000610565Q8NHW4
ENSG00000276070ENST00000613173Q8NHW4
ENSG00000276070ENST00000615418Q8NHW4
ENSG00000276070ENST00000617405Q8NHW4
ENSG00000276070ENST00000617416Q8NHW4
ENSG00000276070ENST00000620055Q8NHW4
ENSG00000276070ENST00000620098Q8NHW4
ENSG00000276070ENST00000620250Q8NHW4
ENSG00000276070ENST00000620576Q8NHW4
ENSG00000276070ENST00000620732Q8NHW4

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Toll-like receptor signaling pathwayKEGGko04620
Cytokine-cytokine receptor interactionKEGGhsa04060
Toll-like receptor signaling pathwayKEGGhsa04620
Chemokine signaling pathwayKEGGko04062
Chemokine signaling pathwayKEGGhsa04062
Cytosolic DNA-sensing pathwayKEGGko04623
Cytosolic DNA-sensing pathwayKEGGhsa04623
Salmonella infectionKEGGko05132
Salmonella infectionKEGGhsa05132
NF-kappa B signaling pathwayKEGGhsa04064
NF-kappa B signaling pathwayKEGGko04064

References

Pubmed IDYearTitleCitations
184649132008A genome-wide association study identifies protein quantitative trait loci (pQTLs).184
173301382007CCL3L1 and CCL4L1: variable gene copy number in adolescents with and without human immunodeficiency virus type 1 (HIV-1) infection.22
173301382007CCL3L1 and CCL4L1: variable gene copy number in adolescents with and without human immunodeficiency virus type 1 (HIV-1) infection.22
192794422009Combinatorial content of CCL3L and CCL4L gene copy numbers influence HIV-AIDS susceptibility in Ukrainian children.21
198989272010Chemokine expression patterns in the systemic and genital tract compartments are associated with HIV-1 infection in women from Benin.16
206591242010Copy number variation in chemokine superfamily: the complex scene of CCL3L-CCL4L genes in health and disease.16
247276462014Comparison of a quantitative Real-Time PCR assay and droplet digital PCR for copy number analysis of the CCL4L genes.10
183680652008Population structure in copy number variation and SNPs in the CCL4L chemokine gene.7
254495362015Genes associated with antibody-dependent cell activation are overexpressed in renal biopsies from patients with antibody-mediated rejection.7
191481422009Copy number variation in the CCL4L gene is associated with susceptibility to acute rejection in lung transplantation.6

Citation

Dessen P

CCL4L2 (C-C motif chemokine ligand 4 like 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61591/ccl4l2-(c-c-motif-chemokine-ligand-4-like-2)