Identity
HGNC
LOCATION
2p15
LOCUSID
ALIAS
CCT-DELTA,Cctd,SRB
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10575
MIM: 605142
HGNC: 1617
Ensembl: ENSG00000115484
Variants:
dbSNP: 10575
ClinVar: 10575
TCGA: ENSG00000115484
COSMIC: CCT4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115484 | ENST00000394440 | P50991 |
| ENSG00000115484 | ENST00000544079 | P50991 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38216268 | 2024 | LINC01234 promoted malignant behaviors of breast cancer cells via hsa-miR-30c-2-3p/CCT4/mTOR signaling pathway. | 0 |
| 38216268 | 2024 | LINC01234 promoted malignant behaviors of breast cancer cells via hsa-miR-30c-2-3p/CCT4/mTOR signaling pathway. | 0 |
| 36102200 | 2022 | CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas. | 3 |
| 36102200 | 2022 | CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas. | 3 |
| 34732665 | 2021 | CCT4 suppression inhibits tumor growth in hepatocellular carcinoma by interacting with Cdc20. | 5 |
| 34732665 | 2021 | CCT4 suppression inhibits tumor growth in hepatocellular carcinoma by interacting with Cdc20. | 5 |
| 24320561 | 2014 | The chaperonin CCT interacts with and mediates the correct folding and activity of three subunits of translation initiation factor eIF3: b, i and h. | 12 |
| 24320561 | 2014 | The chaperonin CCT interacts with and mediates the correct folding and activity of three subunits of translation initiation factor eIF3: b, i and h. | 12 |
| 23612981 | 2013 | Human CCT4 and CCT5 chaperonin subunits expressed in Escherichia coli form biologically active homo-oligomers. | 38 |
| 23612981 | 2013 | Human CCT4 and CCT5 chaperonin subunits expressed in Escherichia coli form biologically active homo-oligomers. | 38 |
Citation
Dessen P
CCT4 (chaperonin containing TCP1 subunit 4)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61601/new-content/case-report-explorer/
