CD1E (CD1e molecule)

2014-11-01  

Identity

HGNC
LOCATION
1q23.1
LOCUSID
ALIAS
CD1A,R2

Other Information

Locus ID:

NCBI: 913
MIM: 188411
HGNC: 1638
Ensembl: ENSG00000158488

Variants:

dbSNP: 913
ClinVar: 913
TCGA: ENSG00000158488
COSMIC: CD1E

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000158488ENST00000368154P15812
ENSG00000158488ENST00000368155P15812
ENSG00000158488ENST00000368156P15812
ENSG00000158488ENST00000368157P15812
ENSG00000158488ENST00000368160P15812
ENSG00000158488ENST00000368161P15812
ENSG00000158488ENST00000368162H0Y345
ENSG00000158488ENST00000368163P15812
ENSG00000158488ENST00000368164P15812
ENSG00000158488ENST00000368165P15812
ENSG00000158488ENST00000368166P15812
ENSG00000158488ENST00000368167P15812
ENSG00000158488ENST00000444681P15812
ENSG00000158488ENST00000452291P15812

Expression (GTEx)

0
1
2
3

Pathways

PathwaySourceExternal ID
Tight junctionKEGGko04530
Hematopoietic cell lineageKEGGko04640
Tight junctionKEGGhsa04530
Hematopoietic cell lineageKEGGhsa04640

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
163113342005Assistance of microbial glycolipid antigen processing by CD1e.91
218443462011Fine tuning by human CD1e of lipid-specific immune responses.25
217884862011Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes.23
227828952012Deciphering the role of CD1e protein in mycobacterial phosphatidyl-myo-inositol mannosides (PIM) processing for presentation by CD1b to T lymphocytes.15
236779982013Dynamics of the antigen-binding grooves in CD1 proteins: reversible hydrophobic collapse in the lipid-free state.12
168202172006Susceptibility to Guillain-Barré syndrome is associated to polymorphisms of CD1 genes.11
182085082008Control of the intracellular pathway of CD1e.7
183258882008Cutting edge: a naturally occurring mutation in CD1e impairs lipid antigen presentation.7
188381762008Susceptibility to Guillain-Barré syndrome is not associated with CD1A and CD1E gene polymorphisms.6
188381762008Susceptibility to Guillain-Barré syndrome is not associated with CD1A and CD1E gene polymorphisms.6

Citation

Dessen P

CD1E (CD1e molecule)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61613/cd1e-(cd1e-molecule)