Identity
HGNC
LOCATION
17q25.1
LOCUSID
ALIAS
CLM-6,CMRF-35,CMRF-35A,CMRF35,CMRF35-A1,CMRF35A,CMRF35A1,IGSF16,LIR
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10871
MIM: 606786
HGNC: 19320
Ensembl: ENSG00000167850
Variants:
dbSNP: 10871
ClinVar: 10871
TCGA: ENSG00000167850
COSMIC: CD300C
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000167850 | ENST00000330793 | Q08708 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Adaptive Immune System | REACTOME | R-HSA-1280218 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | REACTOME | R-HSA-198933 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29906528 | 2019 | CD300c costimulates IgE-mediated basophil activation, and its expression is increased in patients with cow's milk allergy. | 9 |
| 29906528 | 2019 | CD300c costimulates IgE-mediated basophil activation, and its expression is increased in patients with cow's milk allergy. | 9 |
| 30498497 | 2018 | A CD300c-Fc Fusion Protein Inhibits T Cell Immunity. | 7 |
| 30498497 | 2018 | A CD300c-Fc Fusion Protein Inhibits T Cell Immunity. | 7 |
| 27040328 | 2016 | CD300c is uniquely expressed on CD56 bright Natural Killer Cells and differs from CD300a upon ligand recognition. | 15 |
| 27040328 | 2016 | CD300c is uniquely expressed on CD56 bright Natural Killer Cells and differs from CD300a upon ligand recognition. | 15 |
| 23372157 | 2013 | Human CD300C delivers an Fc receptor-γ-dependent activating signal in mast cells and monocytes and differs from CD300A in ligand recognition. | 17 |
| 23571507 | 2013 | CD300c is an activating receptor expressed on human monocytes. | 13 |
| 23372157 | 2013 | Human CD300C delivers an Fc receptor-γ-dependent activating signal in mast cells and monocytes and differs from CD300A in ligand recognition. | 17 |
| 23571507 | 2013 | CD300c is an activating receptor expressed on human monocytes. | 13 |
| 22046970 | 2011 | Differential expression of CD300a/c on human TH1 and TH17 cells. | 12 |
| 22046970 | 2011 | Differential expression of CD300a/c on human TH1 and TH17 cells. | 12 |
| 20656921 | 2010 | Expression and function of CD300 in NK cells. | 35 |
| 20656921 | 2010 | Expression and function of CD300 in NK cells. | 35 |
| 18535206 | 2008 | CD300a/c regulate type I interferon and TNF-alpha secretion by human plasmacytoid dendritic cells stimulated with TLR7 and TLR9 ligands. | 36 |
Citation
Dessen P
CD300C (CD300c molecule)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61619/cd300c-(cd300c-molecule)
