CD300LF (CD300 molecule like family member f)

2014-11-01  

Identity

HGNC
CD300LF
LOCATION
17q25.1
LOCUSID
146722
ALIAS
CD300f,CLM-1,CLM1,IREM-1,IREM1,IgSF13,LMIR3,NKIR

Other Information

Locus ID:

NCBI: 146722
MIM: 609807
HGNC: 29883
Ensembl: ENSG00000186074

Variants:

dbSNP: 146722
ClinVar: 146722
TCGA: ENSG00000186074
COSMIC: CD300LF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186074ENST00000301573Q8TDQ1
ENSG00000186074ENST00000326165Q8TDQ1
ENSG00000186074ENST00000343125Q8TDQ1
ENSG00000186074ENST00000361254Q8TDQ1
ENSG00000186074ENST00000462044Q8TDQ1
ENSG00000186074ENST00000464910Q8TDQ1
ENSG00000186074ENST00000469092Q8TDQ1
ENSG00000186074ENST00000581500Q8TDQ1
ENSG00000186074ENST00000583937J3KS52

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
373023212023CD300f signalling induces inhibitory human monocytes/macrophages.0
373023212023CD300f signalling induces inhibitory human monocytes/macrophages.0
335485782021CD300a and CD300f molecules regulate the function of leukocytes.7
335485782021CD300a and CD300f molecules regulate the function of leukocytes.7
314763192020Differential Lipid Recognition by Mouse versus Human CD300f, Inhibiting Passive Cutaneous Anaphylaxis, Depends on a Single Amino Acid Substitution in its Immunoglobulin-Like Domain.5
321521162020CD300f immunoreceptor is associated with major depressive disorder and decreased microglial metabolic fitness.10
314763192020Differential Lipid Recognition by Mouse versus Human CD300f, Inhibiting Passive Cutaneous Anaphylaxis, Depends on a Single Amino Acid Substitution in its Immunoglobulin-Like Domain.5
321521162020CD300f immunoreceptor is associated with major depressive disorder and decreased microglial metabolic fitness.10
292216852018Role of the Ceramide-CD300f Interaction in Gram-Negative Bacterial Skin Infections.2
292216852018Role of the Ceramide-CD300f Interaction in Gram-Negative Bacterial Skin Infections.2
271184912017A key requirement for CD300f in innate immune responses of eosinophils in colitis.17
271184912017A key requirement for CD300f in innate immune responses of eosinophils in colitis.17
256011892015Rare heterozygous truncating variations and risk of autism spectrum disorder: Whole-exome sequencing of a multiplex family and follow-up study in a Japanese population.4
256011892015Rare heterozygous truncating variations and risk of autism spectrum disorder: Whole-exome sequencing of a multiplex family and follow-up study in a Japanese population.4
230728612013CD300 molecule regulation of human dendritic cell functions.12

Citation

Dessen P

CD300LF (CD300 molecule like family member f)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61623/haematological-explorer/haematological-explorer/welcome