Identity
HGNC
LOCATION
1p36.21
LOCUSID
ALIAS
AOMS4,ELA2A,PE-1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 63036
MIM: 609443
HGNC: 24609
Ensembl: ENSG00000142615
Variants:
dbSNP: 63036
ClinVar: 63036
TCGA: ENSG00000142615
COSMIC: CELA2A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000142615 | ENST00000359621 | P08217 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33674762 | 2021 | Epithelial production of elastase is increased in inflammatory bowel disease and causes mucosal inflammation. | 14 |
| 33674762 | 2021 | Epithelial production of elastase is increased in inflammatory bowel disease and causes mucosal inflammation. | 14 |
| 31358993 | 2019 | CELA2A mutations predispose to early-onset atherosclerosis and metabolic syndrome and affect plasma insulin and platelet activation. | 11 |
| 31358993 | 2019 | CELA2A mutations predispose to early-onset atherosclerosis and metabolic syndrome and affect plasma insulin and platelet activation. | 11 |
| 27358403 | 2016 | Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2. | 18 |
| 27358403 | 2016 | Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2. | 18 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
| 16247445 | 2006 | ELA2 is regulated by hematopoietic transcription factors, but not repressed by AML1-ETO. | 11 |
| 16247445 | 2006 | ELA2 is regulated by hematopoietic transcription factors, but not repressed by AML1-ETO. | 11 |
Citation
Dessen P
CELA2A (chymotrypsin like elastase 2A)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61691/cela2a-(chymotrypsin-like-elastase-2a)
