CENPO (centromere protein O)

2014-11-01  

Identity

HGNC
CENPO
LOCATION
2p23.3
LOCUSID
79172
ALIAS
CENP-O,ICEN-36,MCM21R
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79172
MIM: 611504
HGNC: 28152
Ensembl: ENSG00000138092

Variants:

dbSNP: 79172
ClinVar: 79172
TCGA: ENSG00000138092
COSMIC: CENPO

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138092ENST00000260662Q9BU64
ENSG00000138092ENST00000380834Q9BU64
ENSG00000138092ENST00000473706Q9BU64

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate ForminsREACTOMER-HSA-5663220
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic PrometaphaseREACTOMER-HSA-68877
Resolution of Sister Chromatid CohesionREACTOMER-HSA-2500257
Mitotic Metaphase and AnaphaseREACTOMER-HSA-2555396
Mitotic AnaphaseREACTOMER-HSA-68882
Separation of Sister ChromatidsREACTOMER-HSA-2467813
Chromosome MaintenanceREACTOMER-HSA-73886
Nucleosome assemblyREACTOMER-HSA-774815
Deposition of new CENPA-containing nucleosomes at the centromereREACTOMER-HSA-606279

References

Pubmed IDYearTitleCitations
388907512024High expression levels of centromere protein O participates in cell proliferation of human ovarian cancer.0
388907512024High expression levels of centromere protein O participates in cell proliferation of human ovarian cancer.0
375589872023Prognostic and immune infiltrative biomarkers of CENPO in pan-cancer and its relationship with lung adenocarcinoma cell proliferation and metastasis.1
375589872023Prognostic and immune infiltrative biomarkers of CENPO in pan-cancer and its relationship with lung adenocarcinoma cell proliferation and metastasis.1
335960902021Differential requirements for the CENP-O complex reveal parallel PLK1 kinetochore recruitment pathways.12
335960902021Differential requirements for the CENP-O complex reveal parallel PLK1 kinetochore recruitment pathways.12
314856752019CENPO expression regulates gastric cancer cell proliferation and is associated with poor patient prognosis.12
314856752019CENPO expression regulates gastric cancer cell proliferation and is associated with poor patient prognosis.12
230285902012Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex.21
230285902012Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex.21
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
192868532009CENP-O, a protein localized at the centromere throughout the cell cycle, is a novel target antigen in systemic sclerosis.8
192868532009CENP-O, a protein localized at the centromere throughout the cell cycle, is a novel target antigen in systemic sclerosis.8

Citation

Dessen P

CENPO (centromere protein O)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61709/cenpo-(centromere-protein-o)