Identity
HGNC
LOCATION
15q26.3
LOCUSID
ALIAS
ARCI9,LASS3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 204219
MIM: 615276
HGNC: 23752
Ensembl: ENSG00000154227
Variants:
dbSNP: 204219
ClinVar: 204219
TCGA: ENSG00000154227
COSMIC: CERS3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37128664 | 2023 | A novel homozygous splice site variant in CERS3 causes autosomal recessive congenital ichthyosis. | 0 |
| 37128664 | 2023 | A novel homozygous splice site variant in CERS3 causes autosomal recessive congenital ichthyosis. | 0 |
| 35753729 | 2022 | Ceramide synthase 3 affects invasion and metastasis of hepatocellular carcinoma via the SMAD6 gene. | 2 |
| 35753729 | 2022 | Ceramide synthase 3 affects invasion and metastasis of hepatocellular carcinoma via the SMAD6 gene. | 2 |
| 33684145 | 2021 | β-Sitosterol 3-O-D-glucoside increases ceramide levels in the stratum corneum via the up-regulated expression of ceramide synthase-3 and glucosylceramide synthase in a reconstructed human epidermal keratinization model. | 7 |
| 33684145 | 2021 | β-Sitosterol 3-O-D-glucoside increases ceramide levels in the stratum corneum via the up-regulated expression of ceramide synthase-3 and glucosylceramide synthase in a reconstructed human epidermal keratinization model. | 7 |
| 31958434 | 2020 | Activation of SIRT1 Enhances Epidermal Permeability Barrier Formation through Ceramide Synthase 2- and 3-Dependent Mechanisms. | 7 |
| 32815268 | 2020 | Congenital ichthyosis in Prader-Willi syndrome associated with maternal chromosome 15 uniparental disomy: Case report and review of autosomal recessive conditions unmasked by UPD. | 5 |
| 31958434 | 2020 | Activation of SIRT1 Enhances Epidermal Permeability Barrier Formation through Ceramide Synthase 2- and 3-Dependent Mechanisms. | 7 |
| 32815268 | 2020 | Congenital ichthyosis in Prader-Willi syndrome associated with maternal chromosome 15 uniparental disomy: Case report and review of autosomal recessive conditions unmasked by UPD. | 5 |
| 28875980 | 2017 | Autosomal recessive congenital ichthyosis: CERS3 mutations identified by a next generation sequencing panel targeting ichthyosis genes. | 6 |
| 28875980 | 2017 | Autosomal recessive congenital ichthyosis: CERS3 mutations identified by a next generation sequencing panel targeting ichthyosis genes. | 6 |
| 26887952 | 2016 | Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region. | 28 |
| 26887952 | 2016 | Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region. | 28 |
| 26045466 | 2015 | Male meiotic cytokinesis requires ceramide synthase 3-dependent sphingolipids with unique membrane anchors. | 26 |
Citation
Dessen P
CERS3 (ceramide synthase 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61739/cers3-(ceramide-synthase-3)
