Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10878
MIM: 605336
HGNC: 16980
Ensembl: ENSG00000116785
Variants:
dbSNP: 10878
ClinVar: 10878
TCGA: ENSG00000116785
COSMIC: CFHR3
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Complement cascade | REACTOME | R-HSA-166658 |
| Regulation of Complement cascade | REACTOME | R-HSA-977606 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38524137 | 2024 | Case report: A family of atypical hemolytic uremic syndrome involving a CFH::CFHR1 fusion gene and CFHR3-1-4-2 gene duplication. | 0 |
| 38524137 | 2024 | Case report: A family of atypical hemolytic uremic syndrome involving a CFH::CFHR1 fusion gene and CFHR3-1-4-2 gene duplication. | 0 |
| 37032353 | 2023 | The absence of CFHR3 and CFHR1 genes from the T2T-CHM13 assembly can limit the molecular diagnosis of complement-related diseases. | 2 |
| 37032353 | 2023 | The absence of CFHR3 and CFHR1 genes from the T2T-CHM13 assembly can limit the molecular diagnosis of complement-related diseases. | 2 |
| 34796567 | 2022 | High prevalence of CFHR deletions in Indian women with pregnancy-associated hemolytic uremic syndrome. | 1 |
| 35852862 | 2022 | The miR-590-3p/CFHR3/STAT3 signaling pathway promotes cell proliferation and metastasis in hepatocellular carcinoma. | 5 |
| 36007525 | 2022 | Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations. | 2 |
| 36091034 | 2022 | Anti-factor H antibody and its role in atypical hemolytic uremic syndrome. | 4 |
| 36793547 | 2022 | CFH and CFHR structural variants in atypical Hemolytic Uremic Syndrome: Prevalence, genomic characterization and impact on outcome. | 5 |
| 34796567 | 2022 | High prevalence of CFHR deletions in Indian women with pregnancy-associated hemolytic uremic syndrome. | 1 |
| 35852862 | 2022 | The miR-590-3p/CFHR3/STAT3 signaling pathway promotes cell proliferation and metastasis in hepatocellular carcinoma. | 5 |
| 36007525 | 2022 | Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations. | 2 |
| 36091034 | 2022 | Anti-factor H antibody and its role in atypical hemolytic uremic syndrome. | 4 |
| 36793547 | 2022 | CFH and CFHR structural variants in atypical Hemolytic Uremic Syndrome: Prevalence, genomic characterization and impact on outcome. | 5 |
| 34819935 | 2021 | Complement Factor H-Related 3 Enhanced Inflammation and Complement Activation in Human RPE Cells. | 10 |
Citation
Dessen P
CFHR3 (complement factor H related 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61772/cfhr3-(complement-factor-h-related-3)
