CHAD (chondroadherin)

2014-11-01  

Identity

HGNC
LOCATION
17q21.33
LOCUSID
ALIAS
SLRR4A

Other Information

Locus ID:

NCBI: 1101
MIM: 602178
HGNC: 1909
Ensembl: ENSG00000136457

Variants:

dbSNP: 1101
ClinVar: 1101
TCGA: ENSG00000136457
COSMIC: CHAD

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136457ENST00000258969O15335
ENSG00000136457ENST00000506187H0YA03
ENSG00000136457ENST00000508540O15335

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Focal adhesionKEGGko04510
ECM-receptor interactionKEGGko04512
Focal adhesionKEGGhsa04510
ECM-receptor interactionKEGGhsa04512
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
211270502011Identification and characterization of the integrin alpha2beta1 binding motif in chondroadherin mediating cell attachment.17
195258442009Variation in chondroadherin abundance and fragmentation in the human scoliotic disc.11
282158222017Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin.9
231722282013The C-terminal peptide of chondroadherin modulates cellular activity by selectively binding to heparan sulfate chains.7

Citation

Dessen P

CHAD (chondroadherin)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61786/chad-(chondroadherin)