Identity
HGNC
LOCATION
18p11.21
LOCUSID
ALIAS
C10orf2,C18-ORF2,C18orf2,CHMP1.5,Vps46-2,Vps46B,hVps46-2
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57132
MIM: 606486
HGNC: 24287
Ensembl: ENSG00000255112
Variants:
dbSNP: 57132
ClinVar: 57132
TCGA: ENSG00000255112
COSMIC: CHMP1B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000255112 | ENST00000526991 | Q7LBR1 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Endocytosis | KEGG | ko04144 |
| Endocytosis | KEGG | hsa04144 |
| ESCRT-III complex | KEGG | hsa_M00412 |
| ESCRT-III complex | KEGG | M00412 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35858336 | 2022 | Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1. | 9 |
| 35858336 | 2022 | Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1. | 9 |
| 32251413 | 2020 | Membrane constriction and thinning by sequential ESCRT-III polymerization. | 38 |
| 32251413 | 2020 | Membrane constriction and thinning by sequential ESCRT-III polymerization. | 38 |
| 21616915 | 2011 | Calpain-7 binds to CHMP1B at its second α-helical region and forms a ternary complex with IST1. | 3 |
| 21616915 | 2011 | Calpain-7 binds to CHMP1B at its second α-helical region and forms a ternary complex with IST1. | 3 |
| 19328558 | 2009 | Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population. | 14 |
| 19328558 | 2009 | Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population. | 14 |
| 18997780 | 2008 | Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B. | 118 |
| 18997780 | 2008 | Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B. | 118 |
| 17711858 | 2007 | The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation. | 74 |
| 17711858 | 2007 | The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation. | 74 |
| 16094257 | 2005 | Association analysis of CHMP1.5 genetic variation and bipolar disorder. | 1 |
| 16174732 | 2005 | Structure and ESCRT-III protein interactions of the MIT domain of human VPS4A. | 87 |
| 16094257 | 2005 | Association analysis of CHMP1.5 genetic variation and bipolar disorder. | 1 |
Citation
Dessen P
CHMP1B (charged multivesicular body protein 1B)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61802/chmp1b-(charged-multivesicular-body-protein-1b)
