Identity
HGNC
LOCATION
20q11.22
LOCUSID
ALIAS
C20orf178,CHMP4A,CTPP3,CTRCT31,SNF7,SNF7-2,Shax1,VPS32B,Vps32-2,dJ553F4.4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 128866
MIM: 610897
HGNC: 16171
Ensembl: ENSG00000101421
Variants:
dbSNP: 128866
ClinVar: 128866
TCGA: ENSG00000101421
COSMIC: CHMP4B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101421 | ENST00000217402 | Q9H444 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37931722 | 2024 | CHMP4B and VSP4A reverse GSDMD-mediated pyroptosis by cell membrane remodeling in endometrial carcinoma. | 2 |
| 37931722 | 2024 | CHMP4B and VSP4A reverse GSDMD-mediated pyroptosis by cell membrane remodeling in endometrial carcinoma. | 2 |
| 37487085 | 2023 | HSP90β prevents aging-related cataract formation through regulation of the charged multivesicular body protein (CHMP4B) and p53. | 1 |
| 37487085 | 2023 | HSP90β prevents aging-related cataract formation through regulation of the charged multivesicular body protein (CHMP4B) and p53. | 1 |
| 34281622 | 2021 | The ESCRT-III protein VPS4, but not CHMP4B or CHMP2B, is pathologically increased in familial and sporadic ALS neuronal nuclei. | 10 |
| 34281622 | 2021 | The ESCRT-III protein VPS4, but not CHMP4B or CHMP2B, is pathologically increased in familial and sporadic ALS neuronal nuclei. | 10 |
| 31914703 | 2020 | ESCRT subunit CHMP4B localizes to primary cilia and is required for the structural integrity of the ciliary membrane. | 8 |
| 32585748 | 2020 | Up-regulation of CHMP4B alleviates microglial necroptosis induced by traumatic brain injury. | 11 |
| 33139753 | 2020 | ESCRT-III controls nuclear envelope deformation induced by progerin. | 10 |
| 31914703 | 2020 | ESCRT subunit CHMP4B localizes to primary cilia and is required for the structural integrity of the ciliary membrane. | 8 |
| 32585748 | 2020 | Up-regulation of CHMP4B alleviates microglial necroptosis induced by traumatic brain injury. | 11 |
| 33139753 | 2020 | ESCRT-III controls nuclear envelope deformation induced by progerin. | 10 |
| 28806752 | 2017 | The ESCRT-III pathway facilitates cardiomyocyte release of cBIN1-containing microparticles. | 18 |
| 28806752 | 2017 | The ESCRT-III pathway facilitates cardiomyocyte release of cBIN1-containing microparticles. | 18 |
| 26866605 | 2016 | Structural Study of the HD-PTP Bro1 Domain in a Complex with the Core Region of STAM2, a Subunit of ESCRT-0. | 14 |
Citation
Dessen P
CHMP4B (charged multivesicular body protein 4B)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61806/chmp4b-(charged-multivesicular-body-protein-4b)
