Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79643
MIM: 610901
HGNC: 25675
Ensembl: ENSG00000176108
Variants:
dbSNP: 79643
ClinVar: 79643
TCGA: ENSG00000176108
COSMIC: CHMP6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000176108 | ENST00000325167 | Q96FZ7 |
| ENSG00000176108 | ENST00000571457 | I3L4G8 |
| ENSG00000176108 | ENST00000572525 | I3L3E4 |
| ENSG00000176108 | ENST00000572778 | I3L4A1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 25588614 | 2015 | The VPS-20 subunit of the endosomal sorting complex ESCRT-III exhibits an open conformation in the absence of upstream activation. | 15 |
| 25588614 | 2015 | The VPS-20 subunit of the endosomal sorting complex ESCRT-III exhibits an open conformation in the absence of upstream activation. | 15 |
| 25232011 | 2014 | Inhibition of ESCRT-II-CHMP6 interactions impedes cytokinetic abscission and leads to cell death. | 28 |
| 25232011 | 2014 | Inhibition of ESCRT-II-CHMP6 interactions impedes cytokinetic abscission and leads to cell death. | 28 |
| 22231449 | 2012 | CHMP6 and VPS4A mediate the recycling of Ras to the plasma membrane to promote growth factor signaling. | 16 |
| 22231449 | 2012 | CHMP6 and VPS4A mediate the recycling of Ras to the plasma membrane to promote growth factor signaling. | 16 |
| 19270365 | 2009 | Overexpression of CHMP6 induces cellular oncosis and apoptosis in HeLa cells. | 6 |
| 19686684 | 2009 | Structure and function of the ESCRT-II-III interface in multivesicular body biogenesis. | 70 |
| 19270365 | 2009 | Overexpression of CHMP6 induces cellular oncosis and apoptosis in HeLa cells. | 6 |
| 19686684 | 2009 | Structure and function of the ESCRT-II-III interface in multivesicular body biogenesis. | 70 |
Citation
Dessen P
CHMP6 (charged multivesicular body protein 6)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61807/chmp6-(charged-multivesicular-body-protein-6)
