CHRND (cholinergic receptor nicotinic delta subunit)

2014-11-01  

Identity

HGNC
LOCATION
2q37.1
LOCUSID
ALIAS
ACHRD,CMS2A,CMS3A,CMS3B,CMS3C,FCCMS,SCCMS
FUSION GENES

Other Information

Locus ID:

NCBI: 1144
MIM: 100720
HGNC: 1965
Ensembl: ENSG00000135902

Variants:

dbSNP: 1144
ClinVar: 1144
TCGA: ENSG00000135902
COSMIC: CHRND

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135902ENST00000258385Q07001
ENSG00000135902ENST00000412233F8WBS0
ENSG00000135902ENST00000441621B4DKT6
ENSG00000135902ENST00000446616F8WB46
ENSG00000135902ENST00000449596C9JJV8
ENSG00000135902ENST00000543200Q07001

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Neuroactive ligand-receptor interactionKEGGko04080
Neuroactive ligand-receptor interactionKEGGhsa04080
Neuronal SystemREACTOMER-HSA-112316
Transmission across Chemical SynapsesREACTOMER-HSA-112315
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic CellREACTOMER-HSA-112314
Acetylcholine Binding And Downstream EventsREACTOMER-HSA-181431
Activation of Nicotinic Acetylcholine ReceptorsREACTOMER-HSA-629602
Presynaptic nicotinic acetylcholine receptorsREACTOMER-HSA-622323
Highly sodium permeable acetylcholine nicotinic receptorsREACTOMER-HSA-629587
Postsynaptic nicotinic acetylcholine receptorsREACTOMER-HSA-622327

References

Pubmed IDYearTitleCitations
380878972024CHRND variant in a paternally inherited esophageal atresia and tracheoesophgageal fistula: Report of a case.0
380878972024CHRND variant in a paternally inherited esophageal atresia and tracheoesophgageal fistula: Report of a case.0
323358842020[Clinical and genetic analysis of a patient with slow-channel congenital myasthenic syndrome].0
323358842020[Clinical and genetic analysis of a patient with slow-channel congenital myasthenic syndrome].0
266981742016Investigation of Congenital Myasthenia Reveals Functional Asymmetry of Invariant Acetylcholine Receptor (AChR) Cys-loop Aspartates.7
266981742016Investigation of Congenital Myasthenia Reveals Functional Asymmetry of Invariant Acetylcholine Receptor (AChR) Cys-loop Aspartates.7
242400982014Determinants in the β and δ subunit cytoplasmic loop regulate Golgi trafficking and surface expression of the muscle acetylcholine receptor.6
250805832014A single mutation in the acetylcholine receptor δ-subunit causes distinct effects in two types of neuromuscular synapses.6
242400982014Determinants in the β and δ subunit cytoplasmic loop regulate Golgi trafficking and surface expression of the muscle acetylcholine receptor.6
250805832014A single mutation in the acetylcholine receptor δ-subunit causes distinct effects in two types of neuromuscular synapses.6
234489032013Clinical phenotype and the lack of mutations in the CHRNG, CHRND, and CHRNA1 genes in two Indian families with Escobar syndrome.2
234489032013Clinical phenotype and the lack of mutations in the CHRNG, CHRND, and CHRNA1 genes in two Indian families with Escobar syndrome.2
202019262010Human variation in alcohol response is influenced by variation in neuronal signaling genes.52
205842122010Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans.66
207340642010A large-scale candidate gene association study of age at menarche and age at natural menopause.57

Citation

Dessen P

CHRND (cholinergic receptor nicotinic delta subunit)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61817/chrnd-(cholinergic-receptor-nicotinic-delta-subunit)