Identity
HGNC
LOCATION
11p11.2
LOCUSID
ALIAS
C6ST,GST-1,KS6ST,KSGal6ST,KSST
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8534
MIM: 603797
HGNC: 1969
Ensembl: ENSG00000175264
Variants:
dbSNP: 8534
ClinVar: 8534
TCGA: ENSG00000175264
COSMIC: CHST1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000175264 | ENST00000308064 | O43916 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10804 | imatinib | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PD | 30237583 | |
| PA151958383 | Gastrointestinal Stromal Tumors | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | 30237583 | |
| PA443937 | Drug Toxicity | Disease | VariantAnnotation | associated | PD | 30237583 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 21880669 | 2012 | Novel O-linked glycans containing 6'-sulfo-Gal/GalNAc of MUC1 secreted from human breast cancer YMB-S cells: possible carbohydrate epitopes of KL-6(MUC1) monoclonal antibody. | 21 |
| 22260995 | 2012 | Expression of long-form N-acetylglucosamine-6-O-sulfotransferase 1 in human high endothelial venules. | 5 |
| 21880669 | 2012 | Novel O-linked glycans containing 6'-sulfo-Gal/GalNAc of MUC1 secreted from human breast cancer YMB-S cells: possible carbohydrate epitopes of KL-6(MUC1) monoclonal antibody. | 21 |
| 22260995 | 2012 | Expression of long-form N-acetylglucosamine-6-O-sulfotransferase 1 in human high endothelial venules. | 5 |
| 21041608 | 2011 | Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up. | 58 |
| 21041608 | 2011 | Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up. | 58 |
| 19343046 | 2009 | Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. | 4 |
| 19343046 | 2009 | Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. | 4 |
| 18698629 | 2008 | Spondyloepiphyseal dysplasia, Omani type: further definition of the phenotype. | 16 |
| 18698629 | 2008 | Spondyloepiphyseal dysplasia, Omani type: further definition of the phenotype. | 16 |
| 17690104 | 2007 | Enzymes responsible for synthesis of corneal keratan sulfate glycosaminoglycans. | 25 |
| 17690104 | 2007 | Enzymes responsible for synthesis of corneal keratan sulfate glycosaminoglycans. | 25 |
| 16495484 | 2006 | Upregulation of chondroitin 6-sulphotransferase-1 facilitates Schwann cell migration during axonal growth. | 8 |
| 16495484 | 2006 | Upregulation of chondroitin 6-sulphotransferase-1 facilitates Schwann cell migration during axonal growth. | 8 |
| 15324304 | 2004 | Chondroitin 4-sulphotransferase-1 and chondroitin 6-sulphotransferase-1 are affected differently by uronic acid residues neighbouring the acceptor GalNAc residues. | 1 |
Citation
Dessen P
CHST1 (carbohydrate sulfotransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61819/chst1-(carbohydrate-sulfotransferase-1)
