Identity
HGNC
LOCATION
10q22.1
LOCUSID
ALIAS
C6ST,C6ST1,HSD
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9469
MIM: 603799
HGNC: 1971
Ensembl: ENSG00000122863
Variants:
dbSNP: 9469
ClinVar: 9469
TCGA: ENSG00000122863
COSMIC: CHST3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000122863 | ENST00000373115 | Q7LGC8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA445425 | Prostatic Neoplasms | Disease | ClinicalAnnotation | associated | PD | 20038957 | |
| PA449383 | docetaxel | Chemical | ClinicalAnnotation | associated | PD | 20038957 | |
| PA451644 | thalidomide | Chemical | ClinicalAnnotation | associated | PD | 20038957 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37876363 | 2024 | Indian patients with CHST3-related chondrodysplasia with congenital joint dislocations. | 0 |
| 37876363 | 2024 | Indian patients with CHST3-related chondrodysplasia with congenital joint dislocations. | 0 |
| 37183573 | 2023 | CHST3-related skeletal dysplasia in 14 patients: Identification of 8 novel variants and further expansion of the phenotypic spectrum. | 0 |
| 37621132 | 2023 | Dampening HOTAIR sensitizes the gastric cancer cells to oxaliplatin through miR-195-5p and ABCG2 pathway. | 4 |
| 37183573 | 2023 | CHST3-related skeletal dysplasia in 14 patients: Identification of 8 novel variants and further expansion of the phenotypic spectrum. | 0 |
| 37621132 | 2023 | Dampening HOTAIR sensitizes the gastric cancer cells to oxaliplatin through miR-195-5p and ABCG2 pathway. | 4 |
| 36042462 | 2022 | Biallelic variants in CHST3 cause Spondyloepiphyseal dysplasia with joint dislocations in three Pakistani kindreds. | 1 |
| 36042462 | 2022 | Biallelic variants in CHST3 cause Spondyloepiphyseal dysplasia with joint dislocations in three Pakistani kindreds. | 1 |
| 33495490 | 2021 | Chondroitin 6-sulfate represses keratinocyte proliferation in mouse skin, which is associated with psoriasis. | 8 |
| 33495490 | 2021 | Chondroitin 6-sulfate represses keratinocyte proliferation in mouse skin, which is associated with psoriasis. | 8 |
| 31845005 | 2020 | Abnormal expression of chondroitin sulfate sulfotransferases in the articular cartilage of pediatric patients with Kashin-Beck disease. | 2 |
| 32920014 | 2020 | Lysophosphatidic acid receptor 5 transactivation of TGFBR1 stimulates the mRNA expression of proteoglycan synthesizing genes XYLT1 and CHST3. | 9 |
| 31845005 | 2020 | Abnormal expression of chondroitin sulfate sulfotransferases in the articular cartilage of pediatric patients with Kashin-Beck disease. | 2 |
| 32920014 | 2020 | Lysophosphatidic acid receptor 5 transactivation of TGFBR1 stimulates the mRNA expression of proteoglycan synthesizing genes XYLT1 and CHST3. | 9 |
| 30118797 | 2018 | CHST3 and CHST13 polymorphisms as predictors of bosentan-induced liver toxicity in Japanese patients with pulmonary arterial hypertension. | 3 |
Citation
Dessen P
CHST3 (carbohydrate sulfotransferase 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61822/chst3-(carbohydrate-sulfotransferase-3)
