Identity
HGNC
LOCATION
12p13.31
LOCUSID
ALIAS
CD368,CLEC-6,CLEC6,CLECSF8,Dectin-3,MCL,MPCL
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 338339
MIM: 609964
HGNC: 14554
Ensembl: ENSG00000166527
Variants:
dbSNP: 338339
ClinVar: 338339
TCGA: ENSG00000166527
COSMIC: CLEC4D
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000166527 | ENST00000299665 | Q8WXI8 |
| ENSG00000166527 | ENST00000382064 | A6NHA5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34480018 | 2021 | C-type lectin receptor Dectin3 deficiency balances the accumulation and function of FoxO1-mediated LOX-1(+) M-MDSCs in relieving lupus-like symptoms. | 7 |
| 34480018 | 2021 | C-type lectin receptor Dectin3 deficiency balances the accumulation and function of FoxO1-mediated LOX-1(+) M-MDSCs in relieving lupus-like symptoms. | 7 |
| 32532809 | 2020 | The Mincle/Syk/NF-κB Signaling Circuit Is Essential for Maintaining the Protumoral Activities of Tumor-Associated Macrophages. | 36 |
| 32532809 | 2020 | The Mincle/Syk/NF-κB Signaling Circuit Is Essential for Maintaining the Protumoral Activities of Tumor-Associated Macrophages. | 36 |
| 29616019 | 2018 | The Syk-Coupled C-Type Lectin Receptors Dectin-2 and Dectin-3 Are Involved in Paracoccidioides brasiliensis Recognition by Human Plasmacytoid Dendritic Cells. | 19 |
| 29616019 | 2018 | The Syk-Coupled C-Type Lectin Receptors Dectin-2 and Dectin-3 Are Involved in Paracoccidioides brasiliensis Recognition by Human Plasmacytoid Dendritic Cells. | 19 |
| 24101491 | 2013 | Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL. | 60 |
| 24101491 | 2013 | Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL. | 60 |
| 22689578 | 2012 | The C-type lectin receptor CLECSF8 (CLEC4D) is expressed by myeloid cells and triggers cellular activation through Syk kinase. | 56 |
| 22689578 | 2012 | The C-type lectin receptor CLECSF8 (CLEC4D) is expressed by myeloid cells and triggers cellular activation through Syk kinase. | 56 |
| 14971047 | 2004 | The human C-type lectin CLECSF8 is a novel monocyte/macrophage endocytic receptor. | 36 |
| 14971047 | 2004 | The human C-type lectin CLECSF8 is a novel monocyte/macrophage endocytic receptor. | 36 |
Citation
Dessen P
CLEC4D (C-type lectin domain family 4 member D)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61875/clec4d-(c-type-lectin-domain-family-4-member-d)
