Identity
HGNC
LOCATION
Xq28
LOCUSID
ALIAS
CLCNL2,CLIC2b,MRXS32,XAP121
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1193
MIM: 300138
HGNC: 2063
Ensembl: ENSG00000155962
Variants:
dbSNP: 1193
ClinVar: 1193
TCGA: ENSG00000155962
COSMIC: CLIC2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000155962 | ENST00000321926 | A6PVS0 |
| ENSG00000155962 | ENST00000369449 | O15247 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34229297 | 2021 | Chloride intracellular channel protein 2 is secreted and inhibits MMP14 activity, while preventing tumor cell invasion and metastasis. | 8 |
| 34229297 | 2021 | Chloride intracellular channel protein 2 is secreted and inhibits MMP14 activity, while preventing tumor cell invasion and metastasis. | 8 |
| 29198705 | 2018 | Tilapia and human CLIC2 structures are highly conserved. | 3 |
| 29198705 | 2018 | Tilapia and human CLIC2 structures are highly conserved. | 3 |
| 22814392 | 2012 | An X-linked channelopathy with cardiomegaly due to a CLIC2 mutation enhancing ryanodine receptor channel activity. | 56 |
| 22814392 | 2012 | An X-linked channelopathy with cardiomegaly due to a CLIC2 mutation enhancing ryanodine receptor channel activity. | 56 |
| 18186468 | 2008 | The crystal structure of human chloride intracellular channel protein 2: a disulfide bond with functional implications. | 10 |
| 18186468 | 2008 | The crystal structure of human chloride intracellular channel protein 2: a disulfide bond with functional implications. | 10 |
| 17945253 | 2007 | Structure of the Janus protein human CLIC2. | 28 |
| 18007051 | 2007 | Expression, purification, crystallization and preliminary X-ray diffraction analysis of chloride intracellular channel 2 (CLIC2). | 2 |
| 17945253 | 2007 | Structure of the Janus protein human CLIC2. | 28 |
| 18007051 | 2007 | Expression, purification, crystallization and preliminary X-ray diffraction analysis of chloride intracellular channel 2 (CLIC2). | 2 |
| 15147738 | 2004 | CLIC-2 modulates cardiac ryanodine receptor Ca2+ release channels. | 22 |
| 15147738 | 2004 | CLIC-2 modulates cardiac ryanodine receptor Ca2+ release channels. | 22 |
Citation
Dessen P
CLIC2 (chloride intracellular channel 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61884/clic2-(chloride-intracellular-channel-2)
