Identity
HGNC
LOCATION
1p36.22
LOCUSID
ALIAS
ALC-ALPHA,CDHR12,CST-1,CSTN1,PIK3CD,XB31alpha,alcalpha1,alcalpha2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 22883
MIM: 611321
HGNC: 17447
Ensembl: ENSG00000171603
Variants:
dbSNP: 22883
ClinVar: 22883
TCGA: ENSG00000171603
COSMIC: CLSTN1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000171603 | ENST00000361311 | O94985 |
| ENSG00000171603 | ENST00000377298 | O94985 |
| ENSG00000171603 | ENST00000435891 | Q5SR54 |
| ENSG00000171603 | ENST00000650348 | A0A3B3ITY6 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29093024 | 2017 | Phosphorylation of multiple sites within an acidic region of Alcadein α is required for kinesin-1 association and Golgi exit of Alcadein α cargo. | 8 |
| 29093024 | 2017 | Phosphorylation of multiple sites within an acidic region of Alcadein α is required for kinesin-1 association and Golgi exit of Alcadein α cargo. | 8 |
| 27221318 | 2016 | Calsyntenin-1 mediates hepatitis C virus replication. | 4 |
| 27221318 | 2016 | Calsyntenin-1 mediates hepatitis C virus replication. | 4 |
| 24305499 | 2014 | Increased levels of plasma p3-alcα35, a major fragment of Alcadeinα by γ-secretase cleavage, in Alzheimer's disease. | 7 |
| 24305499 | 2014 | Increased levels of plasma p3-alcα35, a major fragment of Alcadeinα by γ-secretase cleavage, in Alzheimer's disease. | 7 |
| 22434822 | 2012 | Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production. | 71 |
| 22571980 | 2012 | Potential utility of soluble p3-alcadein α plasma levels as a biomarker for sporadic Alzheimer's disease. | 5 |
| 22434822 | 2012 | Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production. | 71 |
| 22571980 | 2012 | Potential utility of soluble p3-alcadein α plasma levels as a biomarker for sporadic Alzheimer's disease. | 5 |
| 21385839 | 2011 | Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1. | 37 |
| 21555518 | 2011 | The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. | 95 |
| 21385839 | 2011 | Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1. | 37 |
| 21555518 | 2011 | The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. | 95 |
| 15037614 | 2004 | Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation. | 34 |
Citation
Dessen P
CLSTN1 (calsyntenin 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61907/clstn1-(calsyntenin-1)
