Identity
HGNC
LOCATION
10q24.32
LOCUSID
ALIAS
ACDP2,HOMG6,HOMGSMR
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54805
MIM: 607803
HGNC: 103
Ensembl: ENSG00000148842
Variants:
dbSNP: 54805
ClinVar: 54805
TCGA: ENSG00000148842
COSMIC: CNNM2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000148842 | ENST00000369875 | Q9H8M5 |
| ENSG00000148842 | ENST00000369878 | Q9H8M5 |
| ENSG00000148842 | ENST00000433628 | Q9H8M5 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37715107 | 2024 | Decreased CNNM2 expression in prefrontal cortex affects sensorimotor gating function, cognition, dendritic spine morphogenesis and risk of schizophrenia. | 0 |
| 38519529 | 2024 | Hypomagnesaemia with varying degrees of extrarenal symptoms as a consequence of heterozygous CNNM2 variants. | 0 |
| 37715107 | 2024 | Decreased CNNM2 expression in prefrontal cortex affects sensorimotor gating function, cognition, dendritic spine morphogenesis and risk of schizophrenia. | 0 |
| 38519529 | 2024 | Hypomagnesaemia with varying degrees of extrarenal symptoms as a consequence of heterozygous CNNM2 variants. | 0 |
| 33600043 | 2021 | The phenotypic and genetic spectrum of patients with heterozygous mutations in cyclin M2 (CNNM2). | 14 |
| 33600043 | 2021 | The phenotypic and genetic spectrum of patients with heterozygous mutations in cyclin M2 (CNNM2). | 14 |
| 32997713 | 2020 | Novel variant in the CNNM2 gene associated with dominant hypomagnesemia. | 8 |
| 32997713 | 2020 | Novel variant in the CNNM2 gene associated with dominant hypomagnesemia. | 8 |
| 30180964 | 2018 | Associations between polymorphisms of the CXCL12 and CNNM2 gene and hypertension risk: A case-control study. | 1 |
| 30341174 | 2018 | The cyclic nucleotide-binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg(2+) efflux activity. | 25 |
| 30180964 | 2018 | Associations between polymorphisms of the CXCL12 and CNNM2 gene and hypertension risk: A case-control study. | 1 |
| 30341174 | 2018 | The cyclic nucleotide-binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg(2+) efflux activity. | 25 |
| 27004590 | 2016 | Genome-wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis-regulation of BORCS7, AS3MT, and NT5C2 in the human brain. | 31 |
| 27068403 | 2016 | Human CNNM2 is not a Mg(2+) transporter per se. | 23 |
| 27401531 | 2016 | Two-stage replication of previous genome-wide association studies of AS3MT-CNNM2-NT5C2 gene cluster region in a large schizophrenia case-control sample from Han Chinese population. | 28 |
Citation
Dessen P
CNNM2 (cyclin and CBS domain divalent metal cation transport mediator 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61943/cnnm2-(cyclin-and-cbs-domain-divalent-metal-cation-transport-mediator-2)
