CNPY4 (canopy FGF signaling regulator 4)

2014-11-01  

Identity

HGNC
CNPY4
LOCATION
7q22.1
LOCUSID
245812
ALIAS
PRAT4B

Other Information

Locus ID:

NCBI: 245812
MIM: 610047
HGNC: 28631
Ensembl: ENSG00000166997

Variants:

dbSNP: 245812
ClinVar: 245812
TCGA: ENSG00000166997
COSMIC: CNPY4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166997ENST00000262932Q8N129
ENSG00000166997ENST00000462193A0A0J9YYJ0
ENSG00000166997ENST00000483756A0A0J9YXE1

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA164713366Tumor necrosis factor alpha (TNF-alpha) inhibitorsChemicalClinicalAnnotationassociatedPD24776844
PA446116Inflammatory Bowel DiseasesDiseaseClinicalAnnotationassociatedPD24776844

References

Pubmed IDYearTitleCitations
224479332012Cell surface trafficking of TLR1 is differentially regulated by the chaperones PRAT4A and PRAT4B.16
224479332012Cell surface trafficking of TLR1 is differentially regulated by the chaperones PRAT4A and PRAT4B.16
163382282006A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression.12
163382282006A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression.12

Citation

Dessen P

CNPY4 (canopy FGF signaling regulator 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61954/cnpy4-(canopy-fgf-signaling-regulator-4)