Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 388753
MIM: 614772
HGNC: 18025
Ensembl: ENSG00000168275
Variants:
dbSNP: 388753
ClinVar: 388753
TCGA: ENSG00000168275
COSMIC: COA6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168275 | ENST00000366612 | Q5JTJ3 |
| ENSG00000168275 | ENST00000366613 | Q5JTJ3 |
| ENSG00000168275 | ENST00000366615 | Q5JTJ3 |
| ENSG00000168275 | ENST00000619305 | Q5JTJ3 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism of proteins | REACTOME | R-HSA-392499 |
| Mitochondrial protein import | REACTOME | R-HSA-1268020 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38395184 | 2024 | Pan-cancer analysis reveals potential immunological and prognostic roles of COA6 in human cancers and preliminary exploration of COA6 in bladder cancer. | 0 |
| 38395184 | 2024 | Pan-cancer analysis reveals potential immunological and prognostic roles of COA6 in human cancers and preliminary exploration of COA6 in bladder cancer. | 0 |
| 36982777 | 2023 | High Expression of COA6 Is Related to Unfavorable Prognosis and Enhanced Oxidative Phosphorylation in Lung Adenocarcinoma. | 3 |
| 36982777 | 2023 | High Expression of COA6 Is Related to Unfavorable Prognosis and Enhanced Oxidative Phosphorylation in Lung Adenocarcinoma. | 3 |
| 32061935 | 2020 | COA6 Facilitates Cytochrome c Oxidase Biogenesis as Thiol-reductase for Copper Metallochaperones in Mitochondria. | 23 |
| 32977416 | 2020 | What Role Does COA6 Play in Cytochrome C Oxidase Biogenesis: A Metallochaperone or Thiol Oxidoreductase, or Both? | 10 |
| 32061935 | 2020 | COA6 Facilitates Cytochrome c Oxidase Biogenesis as Thiol-reductase for Copper Metallochaperones in Mitochondria. | 23 |
| 32977416 | 2020 | What Role Does COA6 Play in Cytochrome C Oxidase Biogenesis: A Metallochaperone or Thiol Oxidoreductase, or Both? | 10 |
| 31515291 | 2019 | Structural and functional characterization of the mitochondrial complex IV assembly factor Coa6. | 12 |
| 31851937 | 2019 | COA6 Is Structurally Tuned to Function as a Thiol-Disulfide Oxidoreductase in Copper Delivery to Mitochondrial Cytochrome c Oxidase. | 25 |
| 31515291 | 2019 | Structural and functional characterization of the mitochondrial complex IV assembly factor Coa6. | 12 |
| 31851937 | 2019 | COA6 Is Structurally Tuned to Function as a Thiol-Disulfide Oxidoreductase in Copper Delivery to Mitochondrial Cytochrome c Oxidase. | 25 |
| 25959673 | 2015 | Cooperation between COA6 and SCO2 in COX2 maturation during cytochrome c oxidase assembly links two mitochondrial cardiomyopathies. | 47 |
| 26160915 | 2015 | COA6 is a mitochondrial complex IV assembly factor critical for biogenesis of mtDNA-encoded COX2. | 53 |
| 25959673 | 2015 | Cooperation between COA6 and SCO2 in COX2 maturation during cytochrome c oxidase assembly links two mitochondrial cardiomyopathies. | 47 |
Citation
Dessen P
COA6 (cytochrome c oxidase assembly factor 6)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61972/coa6-(cytochrome-c-oxidase-assembly-factor-6)
