COG1 (component of oligomeric golgi complex 1)

2014-11-01 Affiliation

Identity

HGNC

COG1

LOCATION

17q25.1

LOCUSID

9382

ALIAS

CDG2G,LDLB

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 9382
MIM: 606973
HGNC: 6545
Ensembl: ENSG00000166685

Variants:

dbSNP: 9382
ClinVar: 9382
TCGA: ENSG00000166685
COSMIC: COG1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000166685	ENST00000299886	Q8WTW3
ENSG00000166685	ENST00000438720	E9PBL8
ENSG00000166685	ENST00000582512	J3QLT5
ENSG00000166685	ENST00000582587	J3KRP4
ENSG00000166685	ENST00000582672	J3QKY9
ENSG00000166685	ENST00000582973	J3KSY3
ENSG00000166685	ENST00000618996	A0A087WVI0

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Metabolism of proteins	REACTOME	R-HSA-392499
Post-translational protein modification	REACTOME	R-HSA-597592
Asparagine N-linked glycosylation	REACTOME	R-HSA-446203
Transport to the Golgi and subsequent modification	REACTOME	R-HSA-948021
ER to Golgi Anterograde Transport	REACTOME	R-HSA-199977
Vesicle-mediated transport	REACTOME	R-HSA-5653656
Membrane Trafficking	REACTOME	R-HSA-199991
COPI-mediated anterograde transport	REACTOME	R-HSA-6807878
Intra-Golgi and retrograde Golgi-to-ER traffic	REACTOME	R-HSA-6811442
Retrograde transport at the Trans-Golgi-Network	REACTOME	R-HSA-6811440
Intra-Golgi traffic	REACTOME	R-HSA-6811438

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
27108190	2016	Mass spectrometric analysis of host cell proteins interacting with dengue virus nonstructural protein 1 in dengue virus-infected HepG2 cells.	7
27412679	2016	Oxidative stress and hemoglobin-cholesterol adduct in renal patients with different LDL phenotypes.	0
27108190	2016	Mass spectrometric analysis of host cell proteins interacting with dengue virus nonstructural protein 1 in dengue virus-infected HepG2 cells.	7
27412679	2016	Oxidative stress and hemoglobin-cholesterol adduct in renal patients with different LDL phenotypes.	0
19008299	2009	Cerebrocostomandibular-like syndrome and a mutation in the conserved oligomeric Golgi complex, subunit 1.	17
19008299	2009	Cerebrocostomandibular-like syndrome and a mutation in the conserved oligomeric Golgi complex, subunit 1.	17
16857184	2006	IntraGolgi distribution of the Conserved Oligomeric Golgi (COG) complex.	25
16857184	2006	IntraGolgi distribution of the Conserved Oligomeric Golgi (COG) complex.	25
11929878	2002	Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp.	8
11929878	2002	Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp.	8

Citation

Dessen P

COG1 (component of oligomeric golgi complex 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61975/cog1-(component-of-oligomeric-golgi-complex-1)