COLEC12 (collectin subfamily member 12)

2014-11-01  

Identity

HGNC
COLEC12
LOCATION
18p11.32
LOCUSID
81035
ALIAS
CLP1,NSR2,SCARA4,SRCL
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 81035
MIM: 607621
HGNC: 16016
Ensembl: ENSG00000158270

Variants:

dbSNP: 81035
ClinVar: 81035
TCGA: ENSG00000158270
COSMIC: COLEC12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000158270ENST00000400256Q5KU26

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
Vesicle-mediated transportREACTOMER-HSA-5653656
Binding and Uptake of Ligands by Scavenger ReceptorsREACTOMER-HSA-2173782
Scavenging by Class A ReceptorsREACTOMER-HSA-3000480

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
385683222024Dysregulated AEBP1 and COLEC12 Genes in Late-Onset Alzheimer's Disease: Insights from Brain Cortex and Peripheral Blood Analysis.0
385683222024Dysregulated AEBP1 and COLEC12 Genes in Late-Onset Alzheimer's Disease: Insights from Brain Cortex and Peripheral Blood Analysis.0
381124092023COLEC12 Promotes Tumor Progression and Is Correlated With Poor Prognosis in Gastric Cancer.1
381124092023COLEC12 Promotes Tumor Progression and Is Correlated With Poor Prognosis in Gastric Cancer.1
328220992020COLEC12 regulates apoptosis of osteosarcoma through Toll-like receptor 4-activated inflammation.12
329099422020Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement.10
328220992020COLEC12 regulates apoptosis of osteosarcoma through Toll-like receptor 4-activated inflammation.12
329099422020Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement.10
294914762018Stromal C-type lectin receptor COLEC12 integrates H. pylori, PGE2-EP2/4 axis and innate immunity in gastric diseases.18
294914762018Stromal C-type lectin receptor COLEC12 integrates H. pylori, PGE2-EP2/4 axis and innate immunity in gastric diseases.18
283179192017Scavenger receptor collectin placenta 1 is a novel receptor involved in the uptake of myelin by phagocytes.24
283179192017Scavenger receptor collectin placenta 1 is a novel receptor involved in the uptake of myelin by phagocytes.24
258198962015Common variants in or near ZNRF1, COLEC12, SCYL1BP1 and API5 are associated with diabetic retinopathy in Chinese patients with type 2 diabetes.18
258198962015Common variants in or near ZNRF1, COLEC12, SCYL1BP1 and API5 are associated with diabetic retinopathy in Chinese patients with type 2 diabetes.18
215618712011Identification of neutrophil granule glycoproteins as Lewis(x)-containing ligands cleared by the scavenger receptor C-type lectin.21

Citation

Dessen P

COLEC12 (collectin subfamily member 12)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62007/colec12-(collectin-subfamily-member-12)