COQ9 (coenzyme Q9)

2014-11-01  

Identity

HGNC
LOCATION
16q21
LOCUSID
ALIAS
C16orf49,COQ10D5
FUSION GENES

Other Information

Locus ID:

NCBI: 57017
MIM: 612837
HGNC: 25302
Ensembl: ENSG00000088682

Variants:

dbSNP: 57017
ClinVar: 57017
TCGA: ENSG00000088682
COSMIC: COQ9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000088682ENST00000262507O75208
ENSG00000088682ENST00000262507A0A024R6U3
ENSG00000088682ENST00000563166H3BPW3
ENSG00000088682ENST00000563391H3BPY0
ENSG00000088682ENST00000564115H3BPC6
ENSG00000088682ENST00000564655H3BNT2
ENSG00000088682ENST00000565964H3BVA5
ENSG00000088682ENST00000567072H3BSJ5
ENSG00000088682ENST00000567933H3BRC0

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Ubiquinol biosynthesisREACTOMER-HSA-2142789

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
363067962022Structure and functionality of a multimeric human COQ7:COQ9 complex.13
363067962022Structure and functionality of a multimeric human COQ7:COQ9 complex.13
341052942021DDIT3 Directs a Dual Mechanism to Balance Glycolysis and Oxidative Phosphorylation during Glutamine Deprivation.14
341052942021DDIT3 Directs a Dual Mechanism to Balance Glycolysis and Oxidative Phosphorylation during Glutamine Deprivation.14
295605822018A family segregating lethal neonatal coenzyme Q(10) deficiency caused by mutations in COQ9.15
295605822018A family segregating lethal neonatal coenzyme Q(10) deficiency caused by mutations in COQ9.15
253394432014Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.64
253394432014Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.64
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
193750582009A nonsense mutation in COQ9 causes autosomal-recessive neonatal-onset primary coenzyme Q10 deficiency: a potentially treatable form of mitochondrial disease.101
193750582009A nonsense mutation in COQ9 causes autosomal-recessive neonatal-onset primary coenzyme Q10 deficiency: a potentially treatable form of mitochondrial disease.101

Citation

Dessen P

COQ9 (coenzyme Q9)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62030/coq9-(coenzyme-q9)