Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84766
MIM: 614178
HGNC: 28657
Ensembl: ENSG00000130038
Variants:
dbSNP: 84766
ClinVar: 84766
TCGA: ENSG00000130038
COSMIC: CRACR2A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000130038 | ENST00000252322 | Q9BSW2 |
| ENSG00000130038 | ENST00000333750 | H7BXT2 |
| ENSG00000130038 | ENST00000440314 | Q9BSW2 |
| ENSG00000130038 | ENST00000535292 | H0YFI5 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30464020 | 2019 | Vigorous Physical Activity Is Associated with Lower Risk of Metastatic-Lethal Progression in Prostate Cancer and Hypomethylation in the CRACR2A Gene. | 13 |
| 31092558 | 2019 | Rab46 integrates Ca(2+) and histamine signaling to regulate selective cargo release from Weibel-Palade bodies. | 14 |
| 30464020 | 2019 | Vigorous Physical Activity Is Associated with Lower Risk of Metastatic-Lethal Progression in Prostate Cancer and Hypomethylation in the CRACR2A Gene. | 13 |
| 31092558 | 2019 | Rab46 integrates Ca(2+) and histamine signaling to regulate selective cargo release from Weibel-Palade bodies. | 14 |
| 30284742 | 2018 | A genome-wide association study identifies an association between variants in EFCAB4B gene and periodontal disease in an Italian isolated population. | 9 |
| 30284742 | 2018 | A genome-wide association study identifies an association between variants in EFCAB4B gene and periodontal disease in an Italian isolated population. | 9 |
| 27221160 | 2017 | A large Rab GTPase family in a small GTPase world. | 19 |
| 27221160 | 2017 | A large Rab GTPase family in a small GTPase world. | 19 |
| 27016526 | 2016 | A large Rab GTPase encoded by CRACR2A is a component of subsynaptic vesicles that transmit T cell activation signals. | 21 |
| 27016526 | 2016 | A large Rab GTPase encoded by CRACR2A is a component of subsynaptic vesicles that transmit T cell activation signals. | 21 |
| 25475730 | 2015 | Expression of a long variant of CRACR2A that belongs to the Rab GTPase protein family in endothelial cells. | 10 |
| 25475730 | 2015 | Expression of a long variant of CRACR2A that belongs to the Rab GTPase protein family in endothelial cells. | 10 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20418871 | 2010 | A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells. | 121 |
| 20708005 | 2010 | Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease. | 137 |
Citation
Dessen P
CRACR2A (calcium release activated channel regulator 2A)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62075/cracr2a-(calcium-release-activated-channel-regulator-2a)
