Identity
HGNC
LOCATION
2q31.3
LOCUSID
ALIAS
EIF4GL,NCM,fSAPb
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57703
MIM: 615186
HGNC: 29322
Ensembl: ENSG00000163510
Variants:
dbSNP: 57703
ClinVar: 57703
TCGA: ENSG00000163510
COSMIC: CWC22
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000163510 | ENST00000404136 | B7WP74 |
| ENSG00000163510 | ENST00000410053 | Q9HCG8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32329775 | 2020 | Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes. | 15 |
| 32345988 | 2020 | Gene expression network analysis of lymph node involvement in colon cancer identifies AHSA2, CDK10, and CWC22 as possible prognostic markers. | 5 |
| 32329775 | 2020 | Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes. | 15 |
| 32345988 | 2020 | Gene expression network analysis of lymph node involvement in colon cancer identifies AHSA2, CDK10, and CWC22 as possible prognostic markers. | 5 |
| 24218557 | 2013 | Crystal structure of the human eIF4AIII-CWC22 complex shows how a DEAD-box protein is inhibited by a MIF4G domain. | 22 |
| 24218557 | 2013 | Crystal structure of the human eIF4AIII-CWC22 complex shows how a DEAD-box protein is inhibited by a MIF4G domain. | 22 |
| 22959432 | 2012 | CWC22 connects pre-mRNA splicing and exon junction complex assembly. | 59 |
| 22961380 | 2012 | Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly. | 52 |
| 23236153 | 2012 | Human spliceosomal protein CWC22 plays a role in coupling splicing to exon junction complex deposition and nonsense-mediated decay. | 44 |
| 22959432 | 2012 | CWC22 connects pre-mRNA splicing and exon junction complex assembly. | 59 |
| 22961380 | 2012 | Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly. | 52 |
| 23236153 | 2012 | Human spliceosomal protein CWC22 plays a role in coupling splicing to exon junction complex deposition and nonsense-mediated decay. | 44 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
Citation
Dessen P
CWC22 (CWC22 spliceosome associated protein homolog)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62207/cwc22-(cwc22-spliceosome-associated-protein-homolog)
