CYB561A3 (cytochrome b561 family member A3)

2014-11-01  

Identity

HGNC
CYB561A3
LOCATION
11q12.2
LOCUSID
220002
ALIAS
CYBASC3,LCYTB
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 220002
MIM: 618757
HGNC: 23014
Ensembl: ENSG00000162144

Variants:

dbSNP: 220002
ClinVar: 220002
TCGA: ENSG00000162144
COSMIC: CYB561A3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162144ENST00000294072Q8NBI2
ENSG00000162144ENST00000426130Q8NBI2
ENSG00000162144ENST00000447532F5H1Q2
ENSG00000162144ENST00000536915Q8NBI2
ENSG00000162144ENST00000537364F5H0P5
ENSG00000162144ENST00000537680F5H121
ENSG00000162144ENST00000539128F5H5Y9
ENSG00000162144ENST00000539890F5H832
ENSG00000162144ENST00000540139F5GX87
ENSG00000162144ENST00000540755F5H240
ENSG00000162144ENST00000542361F5H5L0
ENSG00000162144ENST00000544118F5H466
ENSG00000162144ENST00000545361F5H684
ENSG00000162144ENST00000546151F5GWH8

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
342329872021CYB561A3 is the key lysosomal iron reductase required for Burkitt B-cell growth and survival.11
342329872021CYB561A3 is the key lysosomal iron reductase required for Burkitt B-cell growth and survival.11

Citation

Dessen P

CYB561A3 (cytochrome b561 family member A3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62233/cyb561a3-(cytochrome-b561-family-member-a3)