Identity
HGNC
LOCATION
22q13.2
LOCUSID
ALIAS
CYP2D,CYP2D6,CYP2D7AP,CYP2D7P,CYP2D7P1,CYP2D@,P450C2D,P450DB1,RNA40057
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1564
HGNC: 2624
Ensembl: ENSG00000205702
Variants:
dbSNP: 1564
ClinVar: 1564
TCGA: ENSG00000205702
COSMIC: CYP2D7
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000205702 | ENST00000435101 | F5H6E7 |
| ENSG00000205702 | ENST00000612115 | A0A087X1C5 |
| ENSG00000205702 | ENST00000614967 | A0A087WXN8 |
Expression (GTEx)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA449273 | dextromethorphan | Chemical | VariantAnnotation | not associated | PK | 30040020 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30040020 | 2018 | Functional characterization of CYP2D7 gene variants. | 0 |
| 30040020 | 2018 | Functional characterization of CYP2D7 gene variants. | 0 |
| 17494644 | 2007 | Frequency of the frame-shifting CYP2D7 138delT polymorphism in a large, ethnically diverse sample population. | 2 |
| 17494644 | 2007 | Frequency of the frame-shifting CYP2D7 138delT polymorphism in a large, ethnically diverse sample population. | 2 |
| 12171760 | 2002 | Polymorphism of metabolic genes and susceptibility to occupational chronic manganism. | 7 |
| 12171760 | 2002 | Polymorphism of metabolic genes and susceptibility to occupational chronic manganism. | 7 |
Citation
Dessen P
CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene))
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62253/cyp2d7-(cytochrome-p450-family-2-subfamily-d-member-7-(gene-pseudogene))
