Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 113612
MIM: 610670
HGNC: 20582
Ensembl: ENSG00000155016
Variants:
dbSNP: 113612
ClinVar: 113612
TCGA: ENSG00000155016
COSMIC: CYP2U1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000155016 | ENST00000332884 | Q7Z449 |
| ENSG00000155016 | ENST00000508453 | E9PGH5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36166872 | 2022 | Generation of iPSC lines from hereditary spastic paraplegia 56 (SPG56) patients and family members carrying CYP2U1 mutations. | 1 |
| 36498943 | 2022 | Human Orphan Cytochrome P450 2U1 Catalyzes the ω-Hydroxylation of Leukotriene B(4). | 0 |
| 36166872 | 2022 | Generation of iPSC lines from hereditary spastic paraplegia 56 (SPG56) patients and family members carrying CYP2U1 mutations. | 1 |
| 36498943 | 2022 | Human Orphan Cytochrome P450 2U1 Catalyzes the ω-Hydroxylation of Leukotriene B(4). | 0 |
| 34546337 | 2021 | Implication of folate deficiency in CYP2U1 loss of function. | 10 |
| 34546337 | 2021 | Implication of folate deficiency in CYP2U1 loss of function. | 10 |
| 32006740 | 2020 | Rare novel CYP2U1 and ZFYVE26 variants identified in two Pakistani families with spastic paraplegia. | 7 |
| 32006740 | 2020 | Rare novel CYP2U1 and ZFYVE26 variants identified in two Pakistani families with spastic paraplegia. | 7 |
| 31281085 | 2019 | Whole exome sequencing identifies novel variant underlying hereditary spastic paraplegia in consanguineous Pakistani families. | 4 |
| 31281085 | 2019 | Whole exome sequencing identifies novel variant underlying hereditary spastic paraplegia in consanguineous Pakistani families. | 4 |
| 29034544 | 2018 | CYP2U1 activity is altered by missense mutations in hereditary spastic paraplegia 56. | 8 |
| 29034544 | 2018 | CYP2U1 activity is altered by missense mutations in hereditary spastic paraplegia 56. | 8 |
| 27456766 | 2017 | Spectral and 3D model studies of the interaction of orphan human cytochrome P450 2U1 with substrates and ligands. | 5 |
| 28083596 | 2017 | Cytochrome P450 2U1, a very peculiar member of the human P450s family. | 11 |
| 28725025 | 2017 | An atypical case of SPG56/CYP2U1-related spastic paraplegia presenting with delayed myelination. | 3 |
Citation
Dessen P
CYP2U1 (cytochrome P450 family 2 subfamily U member 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62255/cyp2u1-(cytochrome-p450-family-2-subfamily-u-member-1)
