Identity
HGNC
LOCATION
14q32.2
LOCUSID
ALIAS
CP46,CYP46
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10858
MIM: 604087
HGNC: 2641
Ensembl: ENSG00000036530
Variants:
dbSNP: 10858
ClinVar: 10858
TCGA: ENSG00000036530
COSMIC: CYP46A1
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38592597 | 2024 | The Relationship Between CYP46A1 Polymorphism and Suicide Risk: A Preliminary Investigation. | 0 |
| 38592597 | 2024 | The Relationship Between CYP46A1 Polymorphism and Suicide Risk: A Preliminary Investigation. | 0 |
| 37909961 | 2023 | Cytochrome P450 Family 46 Subfamily A Member 1 Promotes the Progression of Colorectal Cancer by Inducing Tumor Cell Proliferation and Angiogenesis. | 1 |
| 37944529 | 2023 | Cholesterol 24-hydroxylase at the choroid plexus contributes to brain immune homeostasis. | 0 |
| 37909961 | 2023 | Cytochrome P450 Family 46 Subfamily A Member 1 Promotes the Progression of Colorectal Cancer by Inducing Tumor Cell Proliferation and Angiogenesis. | 1 |
| 37944529 | 2023 | Cholesterol 24-hydroxylase at the choroid plexus contributes to brain immune homeostasis. | 0 |
| 34546511 | 2022 | Association of cholesterol 7α-hydroxylase (CYP7A1) promoter polymorphism (rs3808607) and cholesterol 24S-hydroxylase (CYP46A1) intron 2 polymorphism (rs754203) with serum lipids, vitamin D levels, and multiple sclerosis risk in the Turkish population. | 3 |
| 34546511 | 2022 | Association of cholesterol 7α-hydroxylase (CYP7A1) promoter polymorphism (rs3808607) and cholesterol 24S-hydroxylase (CYP46A1) intron 2 polymorphism (rs754203) with serum lipids, vitamin D levels, and multiple sclerosis risk in the Turkish population. | 3 |
| 31777202 | 2020 | Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma. | 32 |
| 32816363 | 2020 | Identification of CYP46A1 as a new regulator of lipid metabolism through CRISPR-based whole-genome screening. | 6 |
| 31777202 | 2020 | Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma. | 32 |
| 32816363 | 2020 | Identification of CYP46A1 as a new regulator of lipid metabolism through CRISPR-based whole-genome screening. | 6 |
| 29516283 | 2018 | CYP46A1 and the APOEε4 Allele Polymorphisms Correlate with the Risk of Alzheimer's Disease. | 8 |
| 29516283 | 2018 | CYP46A1 and the APOEε4 Allele Polymorphisms Correlate with the Risk of Alzheimer's Disease. | 8 |
| 28206854 | 2017 | The relationship between Multidrug Resistance Protein 1(rs1045642) and Cholesterol 24-hydroxylase (rs754203) genes polymorphism with type 2 diabetes mellitus. | 2 |
Citation
Dessen P
CYP46A1 (cytochrome P450 family 46 subfamily A member 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62257/cyp46a1-(cytochrome-p450-family-46-subfamily-a-member-1)
