CYP4F12 (cytochrome P450 family 4 subfamily F member 12)

2014-11-01  

Identity

HGNC
LOCATION
19p13.12
LOCUSID
ALIAS
CYPIVF12,F22329_1
FUSION GENES

Other Information

Locus ID:

NCBI: 66002
MIM: 611485
HGNC: 18857
Ensembl: ENSG00000186204

Variants:

dbSNP: 66002
ClinVar: 66002
TCGA: ENSG00000186204
COSMIC: CYP4F12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186204ENST00000324632Q9HCS2
ENSG00000186204ENST00000517734Q9HCS2
ENSG00000186204ENST00000547332F8VR75
ENSG00000186204ENST00000548237F8VZP1
ENSG00000186204ENST00000548435Q9HCS2
ENSG00000186204ENST00000550308Q9HCS2
ENSG00000186204ENST00000551607F8VU50

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Biological oxidationsREACTOMER-HSA-211859
Phase 1 - Functionalization of compoundsREACTOMER-HSA-211945
Cytochrome P450 - arranged by substrate typeREACTOMER-HSA-211897
Fatty acidsREACTOMER-HSA-211935
EicosanoidsREACTOMER-HSA-211979

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
374148302023CYP4F12 is a potential biomarker and inhibits cell migration of head and neck squamous cell carcinoma via EMT pathway.1
374148302023CYP4F12 is a potential biomarker and inhibits cell migration of head and neck squamous cell carcinoma via EMT pathway.1
343195932021Genetic variants of CYP4F12 gene are associated with glioma susceptibility.3
343195932021Genetic variants of CYP4F12 gene are associated with glioma susceptibility.3
284362812018Terfenadine t-butyl hydroxylation catalyzed by human and marmoset cytochrome P450 3A and 4F enzymes in livers and small intestines.2
284362812018Terfenadine t-butyl hydroxylation catalyzed by human and marmoset cytochrome P450 3A and 4F enzymes in livers and small intestines.2
268453562016Inducible CYP4F12 enhances Hepatitis C virus infection via association with viral nonstructural protein 5B.5
268453562016Inducible CYP4F12 enhances Hepatitis C virus infection via association with viral nonstructural protein 5B.5
180657492008Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.24
180657492008Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.24
161126402005Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8.11
161126402005Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8.11

Citation

Dessen P

CYP4F12 (cytochrome P450 family 4 subfamily F member 12)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62260/cyp4f12-(cytochrome-p450-family-4-subfamily-f-member-12)