Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1582
MIM: 602172
HGNC: 2653
Ensembl: ENSG00000180432
Variants:
dbSNP: 1582
ClinVar: 1582
TCGA: ENSG00000180432
COSMIC: CYP8B1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000180432 | ENST00000316161 | Q9UNU6 |
| ENSG00000180432 | ENST00000437102 | C9JFR9 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36107630 | 2022 | Haploinsufficiency of CYP8B1 associates with increased insulin sensitivity in humans. | 6 |
| 36107630 | 2022 | Haploinsufficiency of CYP8B1 associates with increased insulin sensitivity in humans. | 6 |
| 30465713 | 2019 | Conversion of chenodeoxycholic acid to cholic acid by human CYP8B1. | 13 |
| 30465713 | 2019 | Conversion of chenodeoxycholic acid to cholic acid by human CYP8B1. | 13 |
| 23216301 | 2013 | Single nucleotide polymorphism rs3732860 in the 3'-untranslated region of CYP8B1 gene is associated with gallstone disease in Han Chinese. | 2 |
| 24226095 | 2013 | Retinoic acid-related orphan receptor α regulates diurnal rhythm and fasting induction of sterol 12α-hydroxylase in bile acid synthesis. | 35 |
| 23216301 | 2013 | Single nucleotide polymorphism rs3732860 in the 3'-untranslated region of CYP8B1 gene is associated with gallstone disease in Han Chinese. | 2 |
| 24226095 | 2013 | Retinoic acid-related orphan receptor α regulates diurnal rhythm and fasting induction of sterol 12α-hydroxylase in bile acid synthesis. | 35 |
| 22093981 | 2011 | [Association of single nucleotide polymorphism in human CYP8B1 gene with gallstone disease]. | 1 |
| 22093981 | 2011 | [Association of single nucleotide polymorphism in human CYP8B1 gene with gallstone disease]. | 1 |
| 19898482 | 2009 | Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. | 105 |
| 19898482 | 2009 | Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. | 105 |
| 18660489 | 2008 | Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. | 29 |
| 18660489 | 2008 | Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. | 29 |
| 17585019 | 2007 | Human and murine hepatic sterol-12-alpha-hydroxylase and other xenobiotic metabolism mRNA are upregulated by soy isoflavones. | 6 |
Citation
Dessen P
CYP8B1 (cytochrome P450 family 8 subfamily B member 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62272/cyp8b1-(cytochrome-p450-family-8-subfamily-b-member-1)
