DAAM2 (dishevelled associated activator of morphogenesis 2)

2014-11-01  

Identity

HGNC
LOCATION
6p21.2
LOCUSID
ALIAS
NPHS24,dJ90A20A.1
FUSION GENES

Other Information

Locus ID:

NCBI: 23500
MIM: 606627
HGNC: 18143
Ensembl: ENSG00000146122

Variants:

dbSNP: 23500
ClinVar: 23500
TCGA: ENSG00000146122
COSMIC: DAAM2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000146122ENST00000274867Q86T65
ENSG00000146122ENST00000398904Q86T65
ENSG00000146122ENST00000405961F2Z2Q2
ENSG00000146122ENST00000494405A0A0J9YX09
ENSG00000146122ENST00000538976Q86T65
ENSG00000146122ENST00000633794A0A0J9YYF7

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Wnt signaling pathwayKEGGko04310
Wnt signaling pathwayKEGGhsa04310

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
367906762023The prognostic value of DAAM2 in lower grade glioma, liver cancer, and breast cancer.0
367906762023The prognostic value of DAAM2 in lower grade glioma, liver cancer, and breast cancer.0
359337582022Placental DAAM2 is unaltered in preeclampsia, but upregulated by treatment with proton pump inhibitors.1
359337582022Placental DAAM2 is unaltered in preeclampsia, but upregulated by treatment with proton pump inhibitors.1
336923942021DAAM2 is elevated in the circulation and placenta in pregnancies complicated by fetal growth restriction and is regulated by hypoxia.7
339742412021Disheveled-associated activator of morphogenesis 2 promotes invasion of colorectal cancer by activating PAK1 and promoting MMP7 expression.6
336923942021DAAM2 is elevated in the circulation and placenta in pregnancies complicated by fetal growth restriction and is regulated by hypoxia.7
339742412021Disheveled-associated activator of morphogenesis 2 promotes invasion of colorectal cancer by activating PAK1 and promoting MMP7 expression.6
332326762020DAAM2 Variants Cause Nephrotic Syndrome via Actin Dysregulation.9
332326762020DAAM2 Variants Cause Nephrotic Syndrome via Actin Dysregulation.9
290531012017Daam2 driven degradation of VHL promotes gliomagenesis.12
290531012017Daam2 driven degradation of VHL promotes gliomagenesis.12
262934892016Correlation Between Daam2 Expression Changes and Demyelination in Guillain-Barre Syndrome.5
262934892016Correlation Between Daam2 Expression Changes and Demyelination in Guillain-Barre Syndrome.5
242238032013Metastasis suppressor microRNA-335 targets the formin family of actin nucleators.17

Citation

Dessen P

DAAM2 (dishevelled associated activator of morphogenesis 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62279/daam2-(dishevelled-associated-activator-of-morphogenesis-2)