DAAM2 (dishevelled associated activator of morphogenesis 2)

2014-11-01  

Identity

HGNC
DAAM2
LOCATION
6p21.2
LOCUSID
23500
ALIAS
NPHS24,dJ90A20A.1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23500
MIM: 606627
HGNC: 18143
Ensembl: ENSG00000146122

Variants:

dbSNP: 23500
ClinVar: 23500
TCGA: ENSG00000146122
COSMIC: DAAM2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000146122ENST00000274867Q86T65
ENSG00000146122ENST00000398904Q86T65
ENSG00000146122ENST00000405961F2Z2Q2
ENSG00000146122ENST00000494405A0A0J9YX09
ENSG00000146122ENST00000538976Q86T65
ENSG00000146122ENST00000633794A0A0J9YYF7

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Wnt signaling pathwayKEGGko04310
Wnt signaling pathwayKEGGhsa04310

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
195627782009Wnt antagonist gene polymorphisms and renal cancer.23
242238032013Metastasis suppressor microRNA-335 targets the formin family of actin nucleators.11
262934892016Correlation Between Daam2 Expression Changes and Demyelination in Guillain-Barre Syndrome.3
290531012017Daam2 driven degradation of VHL promotes gliomagenesis.2

Citation

Dessen P

DAAM2 (dishevelled associated activator of morphogenesis 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62279/daam2-(dishevelled-associated-activator-of-morphogenesis-2)