Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8528
MIM: 124450
HGNC: 2727
Ensembl: ENSG00000203797
Variants:
dbSNP: 8528
ClinVar: 8528
TCGA: ENSG00000203797
COSMIC: DDO
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000203797 | ENST00000368923 | Q99489 |
| ENSG00000203797 | ENST00000368924 | Q99489 |
| ENSG00000203797 | ENST00000479373 | F2Z2E0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA451729 | topotecan | Chemical | MultilinkAnnotation | associated | 24444404 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37805834 | 2023 | On the regulation of human D-aspartate oxidase. | 1 |
| 37805834 | 2023 | On the regulation of human D-aspartate oxidase. | 1 |
| 35502931 | 2022 | Genetic variants in DDO and PEX5L in peroxisome-related pathways predict non-small cell lung cancer survival. | 1 |
| 35915065 | 2022 | D-aspartate oxidase gene duplication induces social recognition memory deficit in mice and intellectual disabilities in humans. | 9 |
| 35502931 | 2022 | Genetic variants in DDO and PEX5L in peroxisome-related pathways predict non-small cell lung cancer survival. | 1 |
| 35915065 | 2022 | D-aspartate oxidase gene duplication induces social recognition memory deficit in mice and intellectual disabilities in humans. | 9 |
| 33650155 | 2021 | Cellular studies of the two main isoforms of human d-aspartate oxidase. | 2 |
| 33650155 | 2021 | Cellular studies of the two main isoforms of human d-aspartate oxidase. | 2 |
| 31914658 | 2020 | Structure and kinetic properties of human d-aspartate oxidase, the enzyme-controlling d-aspartate levels in brain. | 10 |
| 31914658 | 2020 | Structure and kinetic properties of human d-aspartate oxidase, the enzyme-controlling d-aspartate levels in brain. | 10 |
| 29729188 | 2018 | Atopic asthma after rhinovirus-induced wheezing is associated with DNA methylation change in the SMAD3 gene promoter. | 24 |
| 29729188 | 2018 | Atopic asthma after rhinovirus-induced wheezing is associated with DNA methylation change in the SMAD3 gene promoter. | 24 |
| 28255110 | 2017 | Methylome-wide association study of whole blood DNA in the Norfolk Island isolate identifies robust loci associated with age. | 22 |
| 28629864 | 2017 | Structure-function relationships in human d-aspartate oxidase: characterisation of variants corresponding to known single nucleotide polymorphisms. | 3 |
| 28255110 | 2017 | Methylome-wide association study of whole blood DNA in the Norfolk Island isolate identifies robust loci associated with age. | 22 |
Citation
Dessen P
DDO (D-aspartate oxidase)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62353/ddo-(d-aspartate-oxidase)
