DECR1 (2,4-dienoyl-CoA reductase 1)

2014-11-01  

Identity

HGNC
LOCATION
8q21.3
LOCUSID
ALIAS
DECR,NADPH,SDR18C1
FUSION GENES

Other Information

Locus ID:

NCBI: 1666
MIM: 222745
HGNC: 2753
Ensembl: ENSG00000104325

Variants:

dbSNP: 1666
ClinVar: 1666
TCGA: ENSG00000104325
COSMIC: DECR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104325ENST00000220764Q16698
ENSG00000104325ENST00000220764A0A024R9D7
ENSG00000104325ENST00000517314E5RHR1
ENSG00000104325ENST00000517597E5RGS6
ENSG00000104325ENST00000517761E5RFV2
ENSG00000104325ENST00000518725E5RID6
ENSG00000104325ENST00000519328E5RGS6
ENSG00000104325ENST00000519410E5RJG7
ENSG00000104325ENST00000520148H0YAW3
ENSG00000104325ENST00000520227E5RJD2
ENSG00000104325ENST00000521603E5RGS6
ENSG00000104325ENST00000522161Q16698

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Mitochondrial Fatty Acid Beta-OxidationREACTOMER-HSA-77289
mitochondrial fatty acid beta-oxidation of unsaturated fatty acidsREACTOMER-HSA-77288

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
374978242023Reduced 2,4-dienoyl-CoA reductase 1 is served as an unfavorable biomarker and is related to immune infiltration in cervical cancer.0
374978242023Reduced 2,4-dienoyl-CoA reductase 1 is served as an unfavorable biomarker and is related to immune infiltration in cervical cancer.0
339098552021Association of whole mtDNA, an NADPH G11914A variant, and haplogroups with high physical performance in an elite military troop.0
342939492021NADPH Oxidases in the Central Nervous System: Regional and Cellular Localization and the Possible Link to Brain Diseases.11
339098552021Association of whole mtDNA, an NADPH G11914A variant, and haplogroups with high physical performance in an elite military troop.0
342939492021NADPH Oxidases in the Central Nervous System: Regional and Cellular Localization and the Possible Link to Brain Diseases.11
3242784020202,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer.62
326866472020Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis.60
3242784020202,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer.62
326866472020Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis.60
243260712014Uric acid induces NADPH oxidase-independent neutrophil extracellular trap formation.60
243260712014Uric acid induces NADPH oxidase-independent neutrophil extracellular trap formation.60
223604202012Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.24
223604202012Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.24
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

DECR1 (2,4-dienoyl-CoA reductase 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62375/decr1-(2-4-dienoyl-coa-reductase-1)