DECR2 (2,4-dienoyl-CoA reductase 2)

2014-11-01  

Identity

HGNC
DECR2
LOCATION
16p13.3
LOCUSID
26063
ALIAS
PDCR,SDR17C1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 26063
MIM: 615839
HGNC: 2754
Ensembl: ENSG00000242612

Variants:

dbSNP: 26063
ClinVar: 26063
TCGA: ENSG00000242612
COSMIC: DECR2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000242612ENST00000219481Q9NUI1
ENSG00000242612ENST00000424398Q4VXZ8
ENSG00000242612ENST00000429116H7C078
ENSG00000242612ENST00000437024G3V0I9
ENSG00000242612ENST00000439661Q9NUI1
ENSG00000242612ENST00000445291G3V0I9
ENSG00000242612ENST00000627716G3V0I9
ENSG00000242612ENST00000631605A0A0J9YXZ6
ENSG00000242612ENST00000633025G3V0I9
ENSG00000242612ENST00000633348A0A0J9YWI0
ENSG00000242612ENST00000633923A0A0J9YY83

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
PeroxisomeKEGGko04146
PeroxisomeKEGGhsa04146
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734

References

Pubmed IDYearTitleCitations
382167202024Peroxisomal β-oxidation enzyme, DECR2, regulates lipid metabolism and promotes treatment resistance in advanced prostate cancer.1
382167202024Peroxisomal β-oxidation enzyme, DECR2, regulates lipid metabolism and promotes treatment resistance in advanced prostate cancer.1

Citation

Dessen P

DECR2 (2,4-dienoyl-CoA reductase 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62376/decr2-(2-4-dienoyl-coa-reductase-2)