Identity
HGNC
LOCATION
20p13
LOCUSID
ALIAS
C20orf8,DEFB-26,DEFB26,HBD26,bA530N10.1,hBD-26
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 81623
HGNC: 15900
Ensembl: ENSG00000125788
Variants:
dbSNP: 81623
ClinVar: 81623
TCGA: ENSG00000125788
COSMIC: DEFB126
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000125788 | ENST00000382398 | Q9BYW3 |
| ENSG00000125788 | ENST00000382398 | A0A384MDP8 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35381696 | 2022 | DEFB126 polymorphisms and association with idiopathic asthenozoospermia in China. | 0 |
| 35381696 | 2022 | DEFB126 polymorphisms and association with idiopathic asthenozoospermia in China. | 0 |
| 31504198 | 2020 | Beta-defensin126 is correlated with sperm motility in fertile and infertile men†. | 10 |
| 31504198 | 2020 | Beta-defensin126 is correlated with sperm motility in fertile and infertile men†. | 10 |
| 30529003 | 2019 | Influence of chewing on expression level of human beta-defensin 2 and secretory immunoglobulin A in the epithelium. | 0 |
| 31474436 | 2019 | The role of DEFB126 variation in male infertility and medically assisted reproduction technique outcome. | 5 |
| 30529003 | 2019 | Influence of chewing on expression level of human beta-defensin 2 and secretory immunoglobulin A in the epithelium. | 0 |
| 31474436 | 2019 | The role of DEFB126 variation in male infertility and medically assisted reproduction technique outcome. | 5 |
| 25721098 | 2015 | Another functional frame-shift polymorphism of DEFB126 (rs11467497) associated with male infertility. | 5 |
| 25721098 | 2015 | Another functional frame-shift polymorphism of DEFB126 (rs11467497) associated with male infertility. | 5 |
| 23229569 | 2013 | Human beta-defensin DEFB126 is capable of inhibiting LPS-mediated inflammation. | 11 |
| 23229569 | 2013 | Human beta-defensin DEFB126 is capable of inhibiting LPS-mediated inflammation. | 11 |
| 22710670 | 2012 | Multifunctional glycoprotein DEFB126--a curious story of defensin-clad spermatozoa. | 36 |
| 22710670 | 2012 | Multifunctional glycoprotein DEFB126--a curious story of defensin-clad spermatozoa. | 36 |
| 21775668 | 2011 | A common mutation in the defensin DEFB126 causes impaired sperm function and subfertility. | 51 |
Citation
Dessen P
DEFB126 (defensin beta 126)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62412/defb126-(defensin-beta-126)
