Identity
HGNC
LOCATION
1q31.3
LOCUSID
ALIAS
C1ORF18,C1orf218,FAM31B
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 163486
MIM: 613292
HGNC: 28404
Ensembl: ENSG00000213047
Variants:
dbSNP: 163486
ClinVar: 163486
TCGA: ENSG00000213047
COSMIC: DENND1B
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Vesicle-mediated transport | REACTOME | R-HSA-5653656 |
| Membrane Trafficking | REACTOME | R-HSA-199991 |
| RAB GEFs exchange GTP for GDP on RABs | REACTOME | R-HSA-8876198 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31608842 | 2019 | Variation at DENND1B and Asthma on the Island of Tristan da Cunha. | 1 |
| 31608842 | 2019 | Variation at DENND1B and Asthma on the Island of Tristan da Cunha. | 1 |
| 28668455 | 2017 | Polymorphisms in DENND1B gene are associated with asthma and atopy phenotypes in Brazilian children. | 8 |
| 28668455 | 2017 | Polymorphisms in DENND1B gene are associated with asthma and atopy phenotypes in Brazilian children. | 8 |
| 26774822 | 2016 | Regulation of T Cell Receptor Signaling by DENND1B in TH2 Cells and Allergic Disease. | 30 |
| 26774822 | 2016 | Regulation of T Cell Receptor Signaling by DENND1B in TH2 Cells and Allergic Disease. | 30 |
| 24347560 | 2015 | DENND1B gene variants associate with elevated exhaled nitric oxide in healthy high-risk neonates. | 1 |
| 26055712 | 2015 | Phosphorylation-dependent Regulation of Connecdenn/DENND1 Guanine Nucleotide Exchange Factors. | 9 |
| 24347560 | 2015 | DENND1B gene variants associate with elevated exhaled nitric oxide in healthy high-risk neonates. | 1 |
| 26055712 | 2015 | Phosphorylation-dependent Regulation of Connecdenn/DENND1 Guanine Nucleotide Exchange Factors. | 9 |
| 22977732 | 2012 | Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer. | 68 |
| 22977732 | 2012 | Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer. | 68 |
| 22065758 | 2011 | Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate. | 64 |
| 22065758 | 2011 | Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate. | 64 |
| 20032318 | 2010 | Variants of DENND1B associated with asthma in children. | 144 |
Citation
Dessen P
DENND1B (DENN domain containing 1B)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62427/dennd1b-(denn-domain-containing-1b)
