DHRS7 (dehydrogenase/reductase 7)

2014-11-01  

Identity

HGNC
LOCATION
14q23.1
LOCUSID
ALIAS
CGI-86,SDR34C1,retDSR4,retSDR4
FUSION GENES

Other Information

Locus ID:

NCBI: 51635
MIM: 612833
HGNC: 21524
Ensembl: ENSG00000100612

Variants:

dbSNP: 51635
ClinVar: 51635
TCGA: ENSG00000100612
COSMIC: DHRS7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100612ENST00000216500Q9Y394
ENSG00000100612ENST00000536410Q9Y394
ENSG00000100612ENST00000554101H0YJ66
ENSG00000100612ENST00000557137H0YJE4
ENSG00000100612ENST00000557185Q9Y394
ENSG00000100612ENST00000557326G3V5J0
ENSG00000100612ENST00000557751H0YJR8

Expression (GTEx)

0
50
100
150
200
250
300

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382012612023Reduction in Nuclear Size by DHRS7 in Prostate Cancer Cells and by Estradiol Propionate in DHRS7-Depleted Cells.0
382012612023Reduction in Nuclear Size by DHRS7 in Prostate Cancer Cells and by Estradiol Propionate in DHRS7-Depleted Cells.0
292163862019An Exome-Wide Association Study Identifies New Susceptibility Loci for Age of Smoking Initiation in African- and European-American Populations.4
292163862019An Exome-Wide Association Study Identifies New Susceptibility Loci for Age of Smoking Initiation in African- and European-American Populations.4
284579672017DHRS7 (SDR34C1) - A new player in the regulation of androgen receptor function by inactivation of 5α-dihydrotestosterone?6
286873842017The identification of new substrates of human DHRS7 by molecular modeling and in vitro testing.2
284579672017DHRS7 (SDR34C1) - A new player in the regulation of androgen receptor function by inactivation of 5α-dihydrotestosterone?6
286873842017The identification of new substrates of human DHRS7 by molecular modeling and in vitro testing.2
264667682016Human DHRS7, promising enzyme in metabolism of steroids and retinoids?11
264667682016Human DHRS7, promising enzyme in metabolism of steroids and retinoids?11
242467602014Biochemical properties of human dehydrogenase/reductase (SDR family) member 7.7
243161912014Purification and reconstitution of human membrane-bound DHRS7 (SDR34C1) from Sf9 cells.1
242467602014Biochemical properties of human dehydrogenase/reductase (SDR family) member 7.7
243161912014Purification and reconstitution of human membrane-bound DHRS7 (SDR34C1) from Sf9 cells.1

Citation

Dessen P

DHRS7 (dehydrogenase/reductase 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62471/dhrs7-(dehydrogenase-reductase-7)