DIS3L (DIS3 like exosome 3-5 exoribonuclease)

2014-11-01  

Identity

HGNC
LOCATION
15q22.31
LOCUSID
ALIAS
DIS3L1
FUSION GENES

Other Information

Locus ID:

NCBI: 115752
MIM: 614183
HGNC: 28698
Ensembl: ENSG00000166938

Variants:

dbSNP: 115752
ClinVar: 115752
TCGA: ENSG00000166938
COSMIC: DIS3L

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166938ENST00000319194Q8TF46
ENSG00000166938ENST00000319212Q8TF46
ENSG00000166938ENST00000524795E9PKI7
ENSG00000166938ENST00000525109E9PS35
ENSG00000166938ENST00000525134E9PIL0
ENSG00000166938ENST00000530537E9PKI7
ENSG00000166938ENST00000530615E9PI27
ENSG00000166938ENST00000532580E9PI20

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
RNA degradationKEGGko03018
RNA degradationKEGGhsa03018

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
205313862010The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L.103
205313892010Dis3-like 1: a novel exoribonuclease associated with the human exosome.56
293213652017Genome-based exome sequencing analysis identifies GYG1, DIS3L and DDRGK1 are associated with myocardial infarction in Koreans.2

Citation

Dessen P

DIS3L (DIS3 like exosome 3-5 exoribonuclease)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62489/dis3l-(dis3-like-exosome-3-5-exoribonuclease)