Identity
HGNC
LOCATION
11q14.1
LOCUSID
ALIAS
PPP1R58,PSD-93,PSD93,chapsyn-110
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1740
MIM: 603583
HGNC: 2901
Ensembl: ENSG00000150672
Variants:
dbSNP: 1740
ClinVar: 1740
TCGA: ENSG00000150672
COSMIC: DLG2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37860969 | 2024 | DLG2 intragenic exonic deletions reinforce the link to neurodevelopmental disorders and suggest a potential association with congenital anomalies and dysmorphism. | 0 |
| 38234042 | 2024 | Glioma stem cell-derived exosomes induce the transformation of astrocytes via the miR-3065-5p/DLG2 signaling axis. | 3 |
| 37860969 | 2024 | DLG2 intragenic exonic deletions reinforce the link to neurodevelopmental disorders and suggest a potential association with congenital anomalies and dysmorphism. | 0 |
| 38234042 | 2024 | Glioma stem cell-derived exosomes induce the transformation of astrocytes via the miR-3065-5p/DLG2 signaling axis. | 3 |
| 35031607 | 2022 | Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variants. | 8 |
| 35217496 | 2022 | DLG2 impairs dsDNA break repair and maintains genome integrity in neuroblastoma. | 2 |
| 35246634 | 2022 | Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2. | 9 |
| 35627244 | 2022 | Enhancing DLG2 Implications in Neuropsychiatric Disorders: Analysis of a Cohort of Eight Patients with 11q14.1 Imbalances. | 3 |
| 35031607 | 2022 | Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variants. | 8 |
| 35217496 | 2022 | DLG2 impairs dsDNA break repair and maintains genome integrity in neuroblastoma. | 2 |
| 35246634 | 2022 | Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2. | 9 |
| 35627244 | 2022 | Enhancing DLG2 Implications in Neuropsychiatric Disorders: Analysis of a Cohort of Eight Patients with 11q14.1 Imbalances. | 3 |
| 34695822 | 2021 | DLG2 Mutations in the Etiology of Pubertal Delay and Idiopathic Hypogonadotropic Hypogonadism. | 2 |
| 34695822 | 2021 | DLG2 Mutations in the Etiology of Pubertal Delay and Idiopathic Hypogonadotropic Hypogonadism. | 2 |
| 32312269 | 2020 | Low DLG2 gene expression, a link between 11q-deleted and MYCN-amplified neuroblastoma, causes forced cell cycle progression, and predicts poor patient survival. | 9 |
Citation
Dessen P
DLG2 (discs large MAGUK scaffold protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62515/dlg2-(discs-large-maguk-scaffold-protein-2)
