Identity
HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
DNAHL1,DNEL2,SPGF39
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8632
MIM: 610063
HGNC: 2946
Ensembl: ENSG00000187775
Variants:
dbSNP: 8632
ClinVar: 8632
TCGA: ENSG00000187775
COSMIC: DNAH17
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000187775 | ENST00000389840 | Q9UFH2 |
| ENSG00000187775 | ENST00000591369 | K7ELN3 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Huntington's disease | KEGG | ko05016 |
| Huntington's disease | KEGG | hsa05016 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37574497 | 2023 | Novel mutations in DNAH17 cause sperm flagellum defects and their influence on ICSI outcome. | 2 |
| 37574497 | 2023 | Novel mutations in DNAH17 cause sperm flagellum defects and their influence on ICSI outcome. | 2 |
| 35932098 | 2022 | Novel compound heterozygous variants of DNAH17 in a Chinese infertile man with multiple morphological abnormalities of sperm flagella. | 2 |
| 35932098 | 2022 | Novel compound heterozygous variants of DNAH17 in a Chinese infertile man with multiple morphological abnormalities of sperm flagella. | 2 |
| 33070343 | 2021 | Novel loss-of-function variants in DNAH17 cause multiple morphological abnormalities of the sperm flagella in humans and mice. | 17 |
| 33070343 | 2021 | Novel loss-of-function variants in DNAH17 cause multiple morphological abnormalities of the sperm flagella in humans and mice. | 17 |
| 31658987 | 2020 | A DNAH17 missense variant causes flagella destabilization and asthenozoospermia. | 54 |
| 31841227 | 2020 | DNAH17 is associated with asthenozoospermia and multiple morphological abnormalities of sperm flagella. | 14 |
| 33423959 | 2020 | Novel compound heterozygous variants in dynein axonemal heavy chain 17 cause asthenoteratospermia with sperm flagellar defects. | 5 |
| 31658987 | 2020 | A DNAH17 missense variant causes flagella destabilization and asthenozoospermia. | 54 |
| 31841227 | 2020 | DNAH17 is associated with asthenozoospermia and multiple morphological abnormalities of sperm flagella. | 14 |
| 33423959 | 2020 | Novel compound heterozygous variants in dynein axonemal heavy chain 17 cause asthenoteratospermia with sperm flagellar defects. | 5 |
| 30575322 | 2019 | The association between methylation patterns of DNAH17 and clinicopathological factors in hepatocellular carcinoma. | 6 |
| 31178125 | 2019 | Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia. | 64 |
| 30575322 | 2019 | The association between methylation patterns of DNAH17 and clinicopathological factors in hepatocellular carcinoma. | 6 |
Citation
Dessen P
DNAH17 (dynein axonemal heavy chain 17)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62548/dnah17-(dynein-axonemal-heavy-chain-17)
