DNAH6 (dynein axonemal heavy chain 6)

2014-11-01  

Identity

HGNC
LOCATION
2p11.2
LOCUSID
ALIAS
DNHL1,Dnahc6,HL-2,HL2
FUSION GENES

Other Information

Locus ID:

NCBI: 1768
MIM: 603336
HGNC: 2951
Ensembl: ENSG00000115423

Variants:

dbSNP: 1768
ClinVar: 1768
TCGA: ENSG00000115423
COSMIC: DNAH6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115423ENST00000389394Q9C0G6

Expression (GTEx)

0
1
2
3
4
5
6
7
8

Pathways

PathwaySourceExternal ID
Huntington's diseaseKEGGko05016
Huntington's diseaseKEGGhsa05016

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
375943002024Novel variants in DNAH6 cause male infertility associated with multiple morphological abnormalities of the sperm flagella (MMAF) and ICSI outcomes.2
375943002024Novel variants in DNAH6 cause male infertility associated with multiple morphological abnormalities of the sperm flagella (MMAF) and ICSI outcomes.2
374248582023A novel frameshift mutation in DNAH6 associated with male infertility and asthenoteratozoospermia.0
374248582023A novel frameshift mutation in DNAH6 associated with male infertility and asthenoteratozoospermia.0
316768302019Identification of DNAH6 mutations in infertile men with multiple morphological abnormalities of the sperm flagella.29
316768302019Identification of DNAH6 mutations in infertile men with multiple morphological abnormalities of the sperm flagella.29
293239292018Variation in Cilia Protein Genes and Progression of Lung Disease in Cystic Fibrosis.7
293239292018Variation in Cilia Protein Genes and Progression of Lung Disease in Cystic Fibrosis.7
290190032017Role of Dynein Axonemal Heavy Chain 6 Gene Expression as a Possible Biomarker for Huntington's Disease: a Translational Study.2
290190032017Role of Dynein Axonemal Heavy Chain 6 Gene Expression as a Possible Biomarker for Huntington's Disease: a Translational Study.2
269188222016DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia.53
269188222016DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia.53

Citation

Dessen P

DNAH6 (dynein axonemal heavy chain 6)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62553/dnah6-(dynein-axonemal-heavy-chain-6)